| Weight | 255.484 g/mol |
|---|---|
| Formula | C8H5Cl3O3 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
2,4,5-trichlorophenoxyacetic acid (35915-18-5, 93-76-5)
2,4,5-T
Score:
#351 in Biology
,
#370 in Chemistry
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- Sigma-Aldrich - 2,4,5-trichlorophenoxyacetic acid20.30 - 82.20 USD
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- Printed double-T monopole antenna for 2.4/5.2 GHz dual-band WLAN operations (IEEE Transactions on Antennas and Propagation, 2003)
- Teratology studies with 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-P-dioxin (Toxicology and Applied Pharmacology, 1971)
- L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor (Canadian Journal of Physiology and Pharmacology, 1989)
- Dihydrotestosterone exerts a depressive influence on the production of interleukin-4 (IL-4), IL-5, and gamma-interferon, but not IL-2 by activated murine T cells (Blood, 1991)
- Prostaglandin E2 at priming of naive CD4+ T cells inhibits acquisition of ability to produce IFN-gamma and IL-2, but not IL-4 and IL-5. (Journal of Immunology, 1995)
- Attenuation of Murine Collagen-Induced Arthritis by a Novel, Potent, Selective Small Molecule Inhibitor of IB Kinase 2, TPCA-1 (2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), Occurs via Reduction of Proinflammatory Cytokines and Antigen-Induced T Cell Proliferation (Journal of Pharmacology and Experimental Therapeutics, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H315: Causes skin irritation
Warning Skin corrosion/irritation - Category 2 - H319: Causes serious eye irritation
Warning Serious eye damage/eye irritation - Category 2A - H335: May cause respiratory irritation
Warning Specific target organ toxicity, single exposure; Respiratory tract irritation - Category 3 - H372: Causes damage to organs through prolonged or repeated exposure
Danger Specific target organ toxicity, repeated exposure - Category 1 - H400: Very toxic to aquatic life
Warning Hazardous to the aquatic environment, acute hazard - Category 1 - H410: Very toxic to aquatic life with long lasting effects
Warning Hazardous to the aquatic environment, long-term hazard - Category 1 - 2,4,5-T
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SMILESC1=C(C(=CC(=C1Cl)Cl)Cl)OCC(=O)O
-
InChIKeySMYMJHWAQXWPDB-UHFFFAOYSA-N
- Pubchem - 2,4,5-trichlorophenoxyacetic acid
- Wikipedia - 2,4,5-T
2,4,5-Trichlorophenoxyacetic acid (also known as 2,4,5-T), a synthetic auxin, is a chlorophenoxy acetic acid herbicide used to defoliate broad-leafed plants. It was developed in the late 1940s and was widely used in the agricultural industry until being phased out, starting in the late 1970s due to toxicity concerns. Agent Orange, a defoliant used by the British in the Malayan Emergency and the U.S.
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Areas of Application
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Trends
Alternate Names
Estimated Properties
| Boiling Point | 323.98 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.59 g/cm3 | EPA T.E.S.T. |
| Flash Point | 172.95 C | EPA T.E.S.T. |
| Water Solubility | 204.69 mg/L | EPA T.E.S.T. |
External Links
Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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