Weight | 311.407 g/mol |
---|---|
Formula | C14H21N3O3S |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 3 |
tolazamide (1156-19-0)
Tolinase · Pharmacia Brand of Tolazamide
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- Sigma-Aldrich - tolazamide338.10 USD
- Fisher Scientific - Search for tolazamide
- TCI - Search for tolazamide
- Effects of tolazamide and exogenous insulin on insulin action in patients with non-insulin-dependent diabetes mellitus (The New England Journal of Medicine, 1986)
- Determining the growth mechanism of tolazamide by induction time measurement (Crystal Growth & Design, 2007)
- Impaired Granulocyte Adherence in Mildly Diabetic Patients: Effects of Tolazamide Treatment (Diabetes, 1980)
- Glucose and Insulin Secretory Response Patterns Following Diet and Tolazamide Therapy in Diabetes (BMJ, 1970)
- Pseudoinsulinoma Syndrome from Inadvertent Tolazamide Ingestion (Annals of Internal Medicine, 1980)
- Combined Therapy of Insulin and Tolazamide Decreases Insulin Requirement and Serum Triglycerides in Obese Patients with Noninsulin-Dependent Diabetes Mellitus (The American Journal of the Medical Sciences, 1987)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Tolinase
- Pharmacia Brand of Tolazamide
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SMILESCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCCCC2
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InChIKeyOUDSBRTVNLOZBN-UHFFFAOYSA-N
- Pubchem - tolazamide
- Wikipedia - tolazamide
Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes. It is part of the sulfonylurea family (ATC A10BB).
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Synthesis
Reactant
+
P-TOLUENESULFONAMIDE
(Schotten-Baumann amide from acid)
P-TOLUENESULFONYL CHLORIDE
+
Reactant
(Sulfonamide)
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