| Weight | 291.734 g/mol |
|---|---|
| Formula | C15H14ClNO3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
zomepirac (33369-31-2)
Zomax · zomepirac sodium · zomepirac potassium
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- Irreversible binding of zomepirac to plasma protein in vitro and in vivo. (Journal of Clinical Investigation, 1986)
- Covalent binding of zomepirac glucuronide to proteins : evidence for a schiff base mechanism (Drug Metabolism and Disposition, 1990)
- Apparent intramolecular acyl migration of zomepirac glucuronide. (Drug Metabolism and Disposition, 1982)
- Examining Product Risk in Context: Market Withdrawal of Zomepirac as a Case Study (JAMA, 1993)
- Effect of probenecid on the formation and elimination of acyl glucuronides: studies with zomepirac (Clinical Pharmacology & Therapeutics, 1985)
- Stability of acyl glucuronides in blood, plasma, and urine: studies with zomepirac. (Drug Metabolism and Disposition, 1985)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Zomax
- zomepirac sodium
- zomepirac potassium
- 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate dihydrate
- McN 2783-21-98
-
SMILESCC1=C(N(C(=C1)CC(=O)O)C)C(=O)C2=CC=C(C=C2)Cl
-
InChIKeyZXVNMYWKKDOREA-UHFFFAOYSA-N
- Pubchem - zomepirac
- Wikipedia - zomepirac
Zomepirac is an orally effective nonsteroidal anti-inflammatory drug (NSAID) that has antipyretic actions. It was developed by McNeil Pharmaceutical, approved by the FDA in 1980, and sold as the sodium salt zomepirac sodium, under the brand name Zomax. Due to its clinical effectiveness, it was preferred by doctors in many situations and obtained a large share of the analgesics market; however, it was subsequently withdrawn in March 1983 due to its tendency to cause serious anaphylaxis in an unpredictable subset of the patient population.
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1,4-DICHLOROBENZENE
(Grignard carbonyl)
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