Weight | 196.681 g/mol |
---|---|
Formula | C10H13ClN2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 1 |
1-(4-Chlorophenyl)piperazine (38212-33-8)
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- Discovery of 1-{2 -[(1S ) -(3 -dimethylamino-propionyl )amino -2 -methylpropyl ] -4 -methyl-phenyl} -4 -[ (2R ) -methyl -3 -(4 -chlorophenyl )-propionyl]piperazine as an orally active antagonist of the melanocortin-4 receptor for the potential treatment of cachexia (Journal of Medicinal Chemistry, 2007)
- Detection of 1-Benzylpiperazine, 1-(3-Trifluoromethylphenyl)-piperazine, and 1-(3-Chlorophenyl)-piperazine in 3,4-Methylenedioxymethamphetamine-Positive Urine Samples (Journal of Analytical Toxicology, 2010)
- Anti-Inflammatory and CNS dEpressant Properties of 1-(4-chlorophenyl)-4-{2-[3-(2-pyridyl) acrylyloxy]-ethyl}-piperazine (DA 1529) (Journal of Pharmaceutical Sciences, 1966)
- Design, synthesis, and anti-allergic activities of novel (R)(-)-1-[(4-chlorophenyl)phenyl methyl]piperazine derivatives (Medicinal Chemistry Research, 2012)
- Synthesis, Spectroscopic Studies and Antifungal Activity of 2-((4(3-Chlorophenyl) piperazine-1-yl)methyl)-3-(8-hydroxy quinolin-5-yl)- 3( H)-quinazolin-4-one Ligand and its Chelates (Journal of Chemistry, 2010)
- Trace level quantification of 1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl genotoxic impurity in trazodone using LCMS/MS (Arabian Journal of Chemistry, 2014)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CN(CCN1)C2=CC=C(C=C2)Cl
-
InChIKeyUNEIHNMKASENIG-UHFFFAOYSA-N
- Pubchem - 1-(4-Chlorophenyl)piperazine
- Wikipedia - Para-Chlorophenylpiperazine
para-Chlorophenylpiperazine (pCPP) is a psychoactive drug of the phenylpiperazine class. It is relatively obscure, with limited human use, and produces slightly psychedelic effects. It has been encountered in illicit capsules as a recreational drug similarly to other piperazines like mCPP.
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Synthesis
21647-84-7
+
Reactant
(Alkylation of primary amines)
Reactant
+
14088-84-7
(Reductive amination)
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