| Weight | 180.226 g/mol |
|---|---|
| Formula | C10H13FN2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
1-(4-Fluorophenyl)piperazine (2252-63-3)
para-fluoro-phenylpiperazine · p-fluoro-phenylpiperazine · 4-fluoro-phenylpiperazine
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- Sigma-Aldrich - 1-(4-Fluorophenyl)piperazine37.50 USD
- Fisher Scientific - Search for 1-(4-Fluorophenyl)piperazine
- TCI - Search for 1-(4-Fluorophenyl)piperazine
- Anxiolytic-Like and Antidepressant-Like Activities of MCL0129 (1-[(S)-2-(4-Fluorophenyl)-2-(4-isopropylpiperadin-1-yl)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine), a Novel and Potent Nonpeptide Antagonist of the Melanocortin-4 Receptor (Journal of Pharmacology and Experimental Therapeutics, 2003)
- Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]-and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909). (Journal of Medicinal Chemistry, 1996)
- Development of Long-Acting Dopamine Transporter Ligands as Potential Cocaine-Abuse Therapeutic Agents: Chiral Hydroxyl-Containing Derivatives of 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (Journal of Medicinal Chemistry, 2002)
- Relationship between in Vivo Occupancy at the Dopamine Transporter and Behavioral Effects of Cocaine, GBR 12909 [1-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and Benztropine Analogs (Journal of Pharmacology and Experimental Therapeutics, 2005)
- Synthesis and in vitro antimicrobial studies of medicinally important novel N-alkyl and N-sulfonyl derivatives of 1-[bis(4-fluorophenyl)-methyl]piperazine (Bioorganic & Medicinal Chemistry, 2006)
- In vivo microdialysis and thermospray tandem mass spectrometry of the dopamine uptake blocker 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR-12909) (Analytical Chemistry, 1990)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - para-fluoro-phenylpiperazine
- p-fluoro-phenylpiperazine
- 4-fluoro-phenylpiperazine
-
SMILESC1CN(CCN1)C2=CC=C(C=C2)F
-
InChIKeyAVJKDKWRVSSJPK-UHFFFAOYSA-N
- Pubchem - 1-(4-Fluorophenyl)piperazine
- Wikipedia - 4-fluoro-phenylpiperazine
para-Fluorophenylpiperazine (pFPP, 4-FPP, 4-Fluorophenylpiperazine; Fluoperazine, Flipiperazine) is a piperazine derivative with mildly psychedelic and euphoriant effects. It has been sold as an ingredient in legal recreational drugs known as "Party pills", initially in New Zealand and subsequently in other countries around the world. pFPP has been found in vitro to act mainly as a 5-HT1A receptor agonist, with some additional affinity for the 5-HT2A and 5-HT2C receptors.
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