Weight | 281.334 g/mol |
---|---|
Formula | C17H16FN3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 3 |
Rotatable Bonds | 2 |
199864-87-4 (199864-87-4)
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SMILESCC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N
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- Wikipedia - rs-127445
RS-127445 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors. The role of the 5-HT2B receptor in the body is still poorly understood, and RS-127445 has been a useful tool in unravelling the function of the various systems in which this receptor is expressed.
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Synthesis
1-Bromo-4-fluoronaphthalene
+
Reactant
(Stille)
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