| Weight | 589.722 g/mol |
|---|---|
| Formula | C30H35N7O4S |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 7 |
Imatinib mesylate (220127-57-1)
Score:
#756 in Biochemistry
,
#2085 in Biology
,
#2558 in Chemistry
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- Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors (The New England Journal of Medicine, 2002)
- Hematologic and Cytogenetic Responses to Imatinib Mesylate in Chronic Myelogenous Leukemia (The New England Journal of Medicine, 2002)
- Correlation of Computed Tomography and Positron Emission Tomography in Patients With Metastatic Gastrointestinal Stromal Tumor Treated at a Single Institution With Imatinib Mesylate: Proposal of New Computed Tomography Response Criteria (Journal of Clinical Oncology, 2007)
- Cardiotoxicity of the cancer therapeutic agent imatinib mesylate (Nature Medicine, 2006)
- Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial (The Lancet, 2009)
- Imatinib Mesylate A New Oral Targeted Therapy (The New England Journal of Medicine, 2002)
-
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SMILESCC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
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- Pubchem - Imatinib mesylate
- Wikipedia - imatinib mesylate
Imatinib, sold under the brand names Gleevec among others, is a medication used to treat cancer. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that is Philadelphia chromosome-positive (Ph+) and certain types of gastrointestinal stromal tumors (GIST), systemic mastocytosis, and myelodysplastic syndrome. It is taken by mouth.
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