Weight | 117.129 g/mol |
---|---|
Formula | C3H3NO2S |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
2,4-THIAZOLIDINEDIONE (2295-31-0)
thiazolidinedione · T-174 · 2,4-thiazolidinedione potassium
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- An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor (PPAR) (Journal of Biological Chemistry, 1995)
- PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. (Diabetes, 1998)
- Thiazolidinedione Use, Fluid Retention, and Congestive Heart Failure A Consensus Statement From the American Heart Association and American Diabetes Association (Circulation, 2003)
- COMPLEX DISTRIBUTION, NOT ABSOLUTE AMOUNT OF ADIPONECTIN, CORRELATES WITH THIAZOLIDINEDIONE-MEDIATED IMPROVEMENT IN INSULIN SENSITIVITY (Journal of Biological Chemistry, 2004)
- Efficacy and Safety of the Human Glucagon-Like Peptide-1 Analog Liraglutide in Combination With Metformin and Thiazolidinedione in Patients With Type 2 Diabetes (LEAD-4 Met+TZD) (Diabetes Care, 2009)
- The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial. (Annals of Internal Medicine, 2007)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - thiazolidinedione
- T-174
- 2,4-thiazolidinedione potassium
-
SMILESC1C(=O)NC(=O)S1
-
InChIKeyZOBPZXTWZATXDG-UHFFFAOYSA-N
- Pubchem - 2,4-THIAZOLIDINEDIONE
- Wikipedia - 2,4-thiazolidinedione
The thiazolidinediones , abbreviated as TZD, also known as glitazones after the prototypical drug ciglitazone, are a class of heterocyclic compounds consisting of a five-membered C3NS ring. The term usually refers to a family of drugs used in the treatment of diabetes mellitus type 2 that were introduced in the late 1990s.
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