| Weight | 71.079 g/mol |
|---|---|
| Formula | C3H5NO |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
azetidin-2-one (930-21-2)
Score:
#56 in Medicinal chemistry
,
#7164 in Chemistry
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- Azetidin-2-one derivatives as inhibitors of thrombin (Bioorganic & Medicinal Chemistry, 1995)
- Stereocontrolled total synthesis of the chiral building block (3S,4R)-3- [(R)-1-hydroxyethyl]-4-acetyloxy-azetidin-2-one: a useful synthon for the synthesis of (+)-thienamycin, carbapenems and penems. (Tetrahedron Letters, 1985)
- 3-Acylamino-azetidin-2-one as a novel class of cysteine proteases inhibitors (Bioorganic & Medicinal Chemistry Letters, 2003)
- Theoretical calculations of b-lactam antibiotics. III: AM1, MNDO, and MINDO/3 calculations of hydrolysis of b-lactam compound (azetidin-2-one ring) (Journal of Computational Chemistry, 1992)
- Microbial generation of (2R,3S)- and (2S,3S)-ethyl 2-benzamidomethyl-3-hydroxybutyrate, a key intermediate in the synthesis of (3S,1R)-3-(1-hydroxyethyl)azetidin-2-one (Journal of The Chemical Society-perkin Transactions 1, 1993)
- Vibrational Circular Dichroism versus Optical Rotation Dispersion and Electronic Circular Dichroism for diastereomers: the stereochemistry of 3-(1-hydroxyethyl)-1-(3-phenylpropanoyl)-azetidin-2-one (Physical Chemistry Chemical Physics, 2012)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CNC1=O
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InChIKeyMNFORVFSTILPAW-UHFFFAOYSA-N
- Pubchem - azetidin-2-one
- Wikipedia - azetidin-2-one
2-Azetidinone is a chemical compound with the molecular formula C3H5NO. It is the simplest -lactam and it forms the central core structure of the -lactam antibiotics and certain cholesterol medications.
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azetidin-2-one
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