2-Chloro-N-isopropylacetamide (2895-21-8)

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Most-cited Publications

• Characterization of Orally Active Nonpeptide Vasopressin V2 Receptor Agonist. Synthesis and Biological Evaluation of Both the (5R)- and (5S)-Enantioisomers of 2-[1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin- 5-yl]-N-isopropylacetamide (Journal of Medicinal Chemistry, 2002)
• Method for preparing 2-chloro-N-(4-fluorophenyl)-N-isopropylacetamide (2013)

Safety

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Trends

Alternate Names

• 2895-21-8
• SMILES
  CC(C)NC(=O)CCl
• InChIKey
  GYPNJSBBOATUPK-UHFFFAOYSA-N

Estimated Properties

External Links

• Pubchem - 2-Chloro-N-isopropylacetamide

Synthesis

CHLOROACETYL CHLORIDE  +  ISOPROPYLAMINE (Schotten-Baumann amide from acid)

2-Chloroacetamide  +  2-CHLOROPROPANE (Alkylation of primary amines)

CHLOROACETONITRILE  +  Isobutene (Ritter reaction)

Synthesis of 2-Chloro-N-isopropylacetamide ›

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2-Chloro-N-isopropylacetamide

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