Phenacyl bromide is the organic compound with the formula C6H5C(O)CH2Br. This colourless solid is a powerful lachrymator as well as a useful precursor to other organic compounds. It is prepared by bromination of acetophenone:
C6H5C(O)CH3 + Br2 C6H5C(O)CH2Br + HBr
The compound was first reported in 1871.