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4'-Hydroxyacetophenone
Weight136.15 g/mol
FormulaC8H8O2
Hydrogen Acceptors2
Hydrogen Donors1
Aromatic Rings1
Rotatable Bonds1

4'-Hydroxyacetophenone (99-93-4)

4-hydroxyacetophenone  ·  1-(4-hydroxyphenyl)ethanone  ·  p-hydroxyacetophenone

Score: #1504 in Physics , #1525 in Biochemistry , #4443 in Chemistry
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Alternate Names

  • 4-hydroxyacetophenone
  • 1-(4-hydroxyphenyl)ethanone
  • p-hydroxyacetophenone
  • piceol
  • para-hydroxyacetophenone
  • SMILES
    CC(=O)C1=CC=C(C=C1)O
  • InChIKey
    TXFPEBPIARQUIG-UHFFFAOYSA-N

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Synthesis

Phenol  +  ACETYL CHLORIDE (Friedel-Crafts acylation)
Acetonitrile  +  4-CHLOROPHENOL (Grignard carbonyl)
4-(1-hydroxyethyl)phenol  +  dimethyl sulfide (Corey-Kim oxidation of secondary alcohols)
Synthesis of 4'-Hydroxyacetophenone ›

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