4'-Hydroxypropiophenone (70-70-2)

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Suppliers

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  25 g
  $13.00

  100 g
  $42.00

  500 g
  $168.00

Most-cited Publications

• Laser flash photolysis study of the reactions of carbonyl triplets with phenols and photochemistry of p-hydroxypropiophenone (Journal of the American Chemical Society, 1981)
• Evaluation of a rapid radiometric differentiation test for the Mycobacterium tuberculosis complex by selective inhibition with p-nitro-alpha-acetylamino-beta-hydroxypropiophenone. (Journal of Clinical Microbiology, 1984)
• Synthesis of 14C Labeled 3-Methoxy-4-Hydroxy --(2-Methoxy-phenoxy)--Hydroxypropiophenone, a Lignin Model Compound (Holzforschung, 1981)
• Evaluation of the p-nitro-alpha-acetylamino-beta-hydroxypropiophenone differential test for identification of Mycobacterium tuberculosis complex. (Journal of Clinical Microbiology, 1985)
• p-Hydroxypropiophenone (PHP) and other so-called pituitary inhibitors (The Journal of Clinical Endocrinology and Metabolism, 1951)
• Propionylation of phenol to 4-hydroxypropiophenone over zeolite H-beta (Journal of Molecular Catalysis A-chemical, 2001)

Safety

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Trends

Alternate Names

• p-hydroxypropiophenone
• 4-hydroxypropiophenone
• para-hydroxypropiophenone
• SMILES
  CCC(=O)C1=CC=C(C=C1)O
• InChIKey
  RARSHUDCJQSEFJ-UHFFFAOYSA-N

External Links

• Pubchem - 4'-Hydroxypropiophenone
• Wikipedia - paroxypropione
  Paroxypropione is a synthetic nonsteroidal estrogen which has been used medically as an antigonadotropin in Spain and Italy but appears to no longer be marketed. It was first synthesized in 1902. The antigonadotropic properties of the drug were discovered in 1951 and it entered clinical use shortly thereafter.

Synthesis

Phenol  +  Propionyl chloride (Friedel-Crafts acylation)

Propanenitrile  +  4-CHLOROPHENOL (Grignard carbonyl)

4-[(S)-1-Hydroxypropyl]phenol  +  dimethyl sulfide (Corey-Kim oxidation of secondary alcohols)

Synthesis of 4'-Hydroxypropiophenone ›

Similar Compounds

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7150-55-2 (7150-55-2)

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1-(4-hydroxyphenyl)dodecan-1-one (2589-74-4)

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1-(4-ethoxyphenyl)propan-1-one (35031-72-2)

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Propiophenone (93-55-0)

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4'-Methoxybutyrophenone (4160-51-4)

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3'-Hydroxypropiophenone (13103-80-5)

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35999-20-3 (35999-20-3)

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1-(4-methoxyphenyl)-3-phenylpropan-1-one (5739-38-8)

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20615-47-8 (20615-47-8)

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1-(4-ethylphenyl)propan-1-one (27465-51-6)

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2-BROMO-4'-HYDROXYACETOPHENONE (2491-38-5)

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4'-Methoxyhexanophenone (6397-82-6)

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BUTYROPHENONE (495-40-9)

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(p-Hydroxyphenyl)glyoxal (24645-80-5)

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6305-04-0 (6305-04-0)

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2',4'-Dihydroxypropiophenone (5792-36-9)

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1,2-Dibenzoylethane (495-71-6)

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(4-Propionyl-phenoxy)-acetic acid (6501-31-1)

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1-(4-isobutylphenyl)propan-1-one (59771-24-3)

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Benzoylacetonitrile (614-16-4)

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Valerophenone (1009-14-9)

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4-Acetylphenyl ether (2615-11-4)

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4'-Phenoxyacetophenone (5031-78-7)

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1,3-diphenylpropan-1-one (1083-30-3)

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2,2-Dimethylpropiophenone (938-16-9)

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2125-49-7 (2125-49-7)

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3-(4-Methoxybenzoyl)propionic acid (3153-44-4)

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Cyclopropyl(4-methoxyphenyl)methanone (7152-03-6)

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2,4'-Dimethylpropiophenone (50390-51-7)

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4-Chlorobutyrophenone (939-52-6)

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3'-Hydroxyacetophenone (121-71-1)

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1-(4-sec-butylphenyl)propan-1-one (96187-76-7)

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4'-Methyl-3-chloropropiophenone (22422-21-5)

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5-(4-Methoxyphenyl)-5-oxopentanoic acid (4609-10-3)

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4'-METHYL-3-PHENYLPROPIOPHENONE (5012-90-8)

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4-(4-ethoxyphenyl)-4-oxobutanoic acid (53623-37-3)

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Octanophenone (1674-37-9)

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4-n-Propylbenzoylacetonitrile (199102-69-7)

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4-Methylbenzoylacetonitrile (7391-28-8)

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1,10-diphenyldecane-1,10-dione (6268-61-7)

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36330-86-6 (36330-86-6)

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30314-44-4 (30314-44-4)

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67828-68-6 (67828-68-6)

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2632-13-5 (2632-13-5)

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4136-21-4 (4136-21-4)

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Sympathone (21213-89-8)

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38425-26-2 (38425-26-2)

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Benzoylacetone (93-91-4)

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1-(4-iodophenyl)propan-1-one (31970-26-0)

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37920-25-5 (37920-25-5)

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3-(4-Hydroxyphenyl)propionitrile (17362-17-3)

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4-PENTYLPHENOL (14938-35-3)

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3',5'-Dihydroxyacetophenone (51863-60-6)

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5325-04-2 (5325-04-2)

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178374-78-2 (178374-78-2)

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2'-Hydroxy-5'-methylpropiophenone (938-45-4)

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4'-Hydroxypropiophenone

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