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2-Chloro-4'-fluoroacetophenone
Weight172.586 g/mol
FormulaC8H6ClFO
Hydrogen Acceptors1
Hydrogen Donors0
Aromatic Rings1
Rotatable Bonds2

2-Chloro-4'-fluoroacetophenone (456-04-2)

alpha-chloro-4-fluoroacetophenone  ·  2-Cl-4'-F-acetophenone

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Alternate Names

  • alpha-chloro-4-fluoroacetophenone
  • 2-Cl-4'-F-acetophenone
  • SMILES
    C1=CC(=CC=C1C(=O)CCl)F
  • InChIKey
    UJZWJOQRSMOFMA-UHFFFAOYSA-N

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Synthesis

CHLOROACETONITRILE  +  1-Chloro-4-fluorobenzene (Grignard carbonyl)
FLUOROBENZENE  +  CHLOROACETYL CHLORIDE (Friedel-Crafts acylation)
126534-42-7  +  dimethyl sulfide (Corey-Kim oxidation of secondary alcohols)
Synthesis of 2-Chloro-4'-fluoroacetophenone ›

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