Weight | 227.22 g/mol |
---|---|
Formula | C9H13N3O4 |
Hydrogen Acceptors | 7 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 2 |
2'-deoxycytidine (56905-41-0, 951-77-9)
Deoxycytidine · Cytosine Deoxyriboside · Cytosine Deoxyribonucleoside
Score:
#1221 in Biochemistry
,
#3052 in Biology
,
#3820 in Chemistry
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- Sigma-Aldrich - 2'-deoxycytidine41.30 - 329.50 USD
- Fisher Scientific - Search for 2'-deoxycytidine
- TCI - 2'-deoxycytidine51.00 - 154.00 USD
- 5-Azacytidine and 5-aza-2-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy (Oncogene, 2002)
- Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2-deoxycytidine (decitabine) in hematopoietic malignancies (Blood, 2004)
- Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. (Proceedings of the National Academy of Sciences of the United States of America, 2003)
- Evaluation of the Antitumor Activity of Gemcitabine (2,2-Difluoro-2-deoxycytidine) (Cancer Research, 1990)
- Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation (Proceedings of the National Academy of Sciences of the United States of America, 1994)
- Low-Dose 5-Aza-2-Deoxycytidine, a DNA Hypomethylating Agent, for the Treatment of High-Risk Myelodysplastic Syndrome: A Multicenter Phase II Study in Elderly Patients (Journal of Clinical Oncology, 2000)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Deoxycytidine
- Cytosine Deoxyriboside
- Cytosine Deoxyribonucleoside
-
SMILESC1C(C(OC1N2C=CC(=NC2=O)N)CO)O
-
InChIKeyCKTSBUTUHBMZGZ-UHFFFAOYSA-N
- Pubchem - 2'-deoxycytidine
- Wikipedia - Deoxycytidine
Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the 2' position. Deoxycytidine can be phosphorylated by deoxycytidine kinase (DCK).
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