Weight | 246.194 g/mol |
---|---|
Formula | C9H11FN2O5 |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 1 |
doxifluridine (3094-09-5)
doxyfluridine · Ro 21-9738 · Furtulon
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- Positive Correlation between the Efficacy of Capecitabine and Doxifluridine and the Ratio of Thymidine Phosphorylase to Dihydropyrimidine Dehydrogenase Activities in Tumors in Human Cancer Xenografts (Cancer Research, 1998)
- Prognostic Significance of miR-181b and miR-21 in Gastric Cancer Patients Treated with S-1/Oxaliplatin or Doxifluridine/Oxaliplatin (PLOS ONE, 2011)
- Role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in tumour progression and sensitivity to doxifluridine in gastric cancer patients (European Journal of Cancer, 2002)
- A novel organicinorganic microhybrids containing anticancer agent doxifluridine and layered double hydroxides: Structure and controlled release properties (Chemical Engineering Science, 2010)
- A prospective randomized study of gemcitabine with doxifluridine versus paclitaxel with doxifluridine in concurrent chemoradiotherapy for locally advanced pancreatic cancer (International Journal of Radiation Oncology Biology Physics, 2004)
- Doxifluridine and leucovorin: an oral treatment combination in advanced colorectal cancer. (Journal of Clinical Oncology, 1995)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - doxyfluridine
- Ro 21-9738
- Furtulon
- 5'-DFUR
- 5'-deoxy-5-fluorouridine
- 5'-deoxy-5'-fluorouridine
- 5'-fluoro-5'-deoxyuridine
-
SMILESCC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O
-
InChIKeyZWAOHEXOSAUJHY-UHFFFAOYSA-N
- Pubchem - doxifluridine
- Wikipedia - doxifluridine
Doxifluridine is a second generation nucleoside analog prodrug developed by Roche and used as a cytostatic agent in chemotherapy in several Asian countries including China and South Korea. Doxifluridine is not FDA-approved for use in the USA. It is currently being evaluated in several clinical trials as a stand alone or combination therapy treatment.
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