Weight | 218.229 g/mol |
---|---|
Formula | C9H16NO5- |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 3 |
Aromatic Rings | 0 |
Rotatable Bonds | 6 |
pantothenate (20938-62-9)
Score:
#405 in Biochemistry
,
#1384 in Biology
,
#1619 in Chemistry
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- A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome (Nature Genetics, 2001)
- A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis (Nature Medicine, 2002)
- Cloning and Functional Expression of a cDNA Encoding a Mammalian Sodium-dependent Vitamin Transporter Mediating the Uptake of Pantothenate, Biotin, and Lipoate (Journal of Biological Chemistry, 1998)
- Pallidal stimulation improves pantothenate kinaseassociated neurodegeneration (Annals of Neurology, 2005)
- Pantothenate Kinase Regulation of the Intracellular Concentration of Coenzyme A (Journal of Biological Chemistry, 2000)
- The effects of pantothenate deficiency and acetate addition on anaerobic batch fermentation of glucose by Saccharomyces cerevisiae (Applied Microbiology and Biotechnology, 1996)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
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- Pubchem - pantothenate
- Wikipedia - pantothenate
Pantothenic acid, also called vitamin B5 (a B vitamin), is a water-soluble vitamin. Pantothenic acid is an essential nutrient. Animals require pantothenic acid in order to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats.
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Synthesis
3-Hydroxy-2,2-dimethylpropanal
+
Reactant
(Grignard alcohol)
Reactant
+
3-Aminopropanoate
(Schotten-Baumann amide from acid)
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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