| Weight | 155.197 g/mol |
|---|---|
| Formula | C8H13NO2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
bemegride (64-65-3)
Megimide · Ethylmethylglutarimide · Methetharimide
Score:
#169 in Neurology
,
#756 in Neuroscience
,
#3337 in Biology
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- Neurophysiological mechanisms involved in grand mal seizures induced by metrazol and megimide (Electroencephalography and Clinical Neurophysiology, 1971)
- Discriminative stimulus properties of pentylenetetrazol and bemegride: Some generalization and antagonism tests (Psychopharmacology, 1979)
- Acute Glutethimide (Doriden) Poisoning The Use of Bemegride (Megimide) and Hemodialysis (JAMA Internal Medicine, 1958)
- Antagonism of gamma-aminobutyric acid and muscimol by picrotoxin, bicuculline, strychnine, bemegride, leptazol, D-tubocurarine and theophylline in the isolated olfactory cortex. (Naunyn-schmiedebergs Archives of Pharmacology, 1982)
- Diazepam as a discriminative cue: Its antagonism by bemegride (European Journal of Pharmacology, 1975)
- Megimide and metrazol A comparison of their convulsant properties in man and cat (Electroencephalography and Clinical Neurophysiology, 1958)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Megimide
- Ethylmethylglutarimide
- Methetharimide
-
SMILESCCC1(CC(=O)NC(=O)C1)C
-
InChIKeyORRZGUBHBVWWOP-UHFFFAOYSA-N
- Pubchem - bemegride
- Wikipedia - bemegride
Bemegride (trademarked as Megimide) is a central nervous system stimulant and antidote for barbiturate poisoning as its chemoreceptor agonism increases mean tidal volume, thereby increasing respiration and the concentration of O2 in blood although it may be theoretically used as a supportive measure in treating any depressant overdose. The drug was first synthesized in 1911. As with other chemoreceptor agonists, it is a potent emetic at doses above those normally used in management of barbiturate overdose although emesis and aspiration are a concern during treatment.
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bemegride
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