| Weight | 241.251 g/mol |
|---|---|
| Formula | C9H15N5O3 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
Sapropterin (62989-33-7)
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- Efficacy of sapropterin dihydrochloride (tetrahydrobiopterin, 6R-BH4) for reduction of phenylalanine concentration in patients with phenylketonuria: a phase III randomised placebo-controlled study (The Lancet, 2007)
- Efficacy of sapropterin dihydrochloride in increasing phenylalanine tolerance in children with phenylketonuria: a phase III, randomized, double-blind, placebo-controlled study. (The Journal of Pediatrics, 2009)
- The response of patients with phenylketonuria and elevated serum phenylalanine to treatment with oral sapropterin dihydrochloride (6R-tetrahydrobiopterin): a phase II, multicentre, open-label, screening study (Journal of Inherited Metabolic Disease, 2007)
- Optimizing the use of sapropterin (BH4) in the management of phenylketonuria (Molecular Genetics and Metabolism, 2009)
- Safety and efficacy of 22 weeks of treatment with sapropterin dihydrochloride in patients with phenylketonuria (American Journal of Medical Genetics Part A, 2008)
- Sapropterin therapy increases stability of blood phenylalanine levels in patients with BH4-responsive phenylketonuria (PKU) (Molecular Genetics and Metabolism, 2010)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C(C1CNC2=C(N1)C(=O)N=C(N2)N)O)O
-
InChIKeyFNKQXYHWGSIFBK-UHFFFAOYSA-N
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