| Weight | 237.219 g/mol |
|---|---|
| Formula | C9H11N5O3 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
6-Biopterin (22150-76-1, 9036-22-0)
Biopterin · 2-Amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone · Dictyopterin
Score:
#754 in Neuroscience
,
#1388 in Biochemistry
,
#3334 in Biology
,
#4156 in Chemistry
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- Analysis of reduced forms of biopterin in biological tissues and fluids (Analytical Biochemistry, 1980)
- Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages. (Journal of Biological Chemistry, 1989)
- Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages (Blood, 1995)
- Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase (FEBS Letters, 1991)
- Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta. (Diabetes, 1999)
- An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regions (Neuroscience Letters, 1988)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Biopterin
- 2-Amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone
- Dictyopterin
- Orinapterin
-
SMILESCC(C(C1=CN=C2C(=N1)C(=O)N=C(N2)N)O)O
-
InChIKeyLHQIJBMDNUYRAM-UHFFFAOYSA-N
- Pubchem - 6-Biopterin
- Wikipedia - Biopterin
Biopterins are pterin derivatives which function as endogenous enzyme cofactors in many species of animals and in some bacteria and fungi. Biopterins act as cofactors for aromatic amino acid hydroxylases (AAAH), which are involved in the synthesis of a number of neurotransmitters including dopamine, norepinephrine, epinepherine, and serotonin, along with several trace amines; nitric oxide synthesis also utilizes biopterin derivatives as cofactors. In humans, tetrahydrobiopterin is the endogenous cofactor for AAAH enzymes.
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6-Biopterin
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