| Weight | 253.218 g/mol |
|---|---|
| Formula | C9H11N5O4 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
neopterin (2009-64-5, 670-65-5)
Neopterin, (erythro-L)-Isomer · Neopterin, (R*, R*)-Isomer · 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone
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- Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma. (Journal of Experimental Medicine, 1984)
- Neopterin as a marker for activated cell-mediated immunity: Application in HIV infection (Immunology Today, 1988)
- Neopterin as a marker for immune system activation. (Current Drug Metabolism, 2002)
- Neopterin as Marker for Activation of Cellular Immunity: Immunologic Basis and Clinical Application (Advances in Clinical Chemistry, 1989)
- The Role of Neopterin as a Monitor of Cellular Immune Activation in Transplantation, Inflammatory, Infectious, and Malignant Diseases (Critical Reviews in Clinical Laboratory Sciences, 1992)
- Increased neopterin and interferon-gamma secretion and lower availability of L-tryptophan in major depression: further evidence for an immune response. (Psychiatry Research-neuroimaging, 1994)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Neopterin, (erythro-L)-Isomer
- Neopterin, (R*, R*)-Isomer
- 2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone
- Monapterin
- Umanopterin
- Neopterin, (erythro-D)-Isomer
- Neopterin, (threo-D)-Isomer
- Neopterin, (threo-L)-Isomer
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SMILESC1=C(N=C2C(=N1)NC(=NC2=O)N)C(C(CO)O)O
-
InChIKeyBMQYVXCPAOLZOK-UHFFFAOYSA-N
- Pubchem - neopterin
- Wikipedia - neopterin
Neopterin is a catabolic product of guanosine triphosphate (GTP), a purine nucleotide. Neopterin belongs to the chemical group known as pteridines. It is synthesised by human macrophages upon stimulation with the cytokine interferon-gamma and is indicative of a pro-inflammatory immune status.
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