| Weight | 247.726 g/mol |
|---|---|
| Formula | C10H18ClN3O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
semustine
33073-59-5, 33185-87-4, 13909-09-6
"What do you need help with?"
LabBot
- Sigma-Aldrich - semustine148.00 USD
- Fisher Scientific - Search for semustine
- TCI - Search for semustine
- Leukemia and Preleukemia after Adjuvant Treatment of Gastrointestinal Cancer with Semustine (Methyl-CCNU) (The New England Journal of Medicine, 1983)
- Chemotherapy of advanced colorectal carcinoma: fluorouracil alone vs. two drug combinations using fluorouracil, hydroxyurea, semustine, dacarbazine, razoxane, and mitomycin. A phase III trial by the Eastern Cooperative Oncology Group (EST: 1278). (American Journal of Clinical Oncology, 1984)
- Leukemia after adjuvant chemotherapy with semustine (methyl-CCNU)--evidence of a dose-response effect. (The New England Journal of Medicine, 1986)
- Candidate genes influencing sensitivity and resistance of human glioblastoma to Semustine. (Brain Research Bulletin, 2011)
- Chemotherapy of malignant hepatomas with sequential intraarterial doxorubicin and systemic 5fluorouracil and semustine (Cancer, 1988)
- Nephrotoxicity of semustine. (Cancer treatment reports, 1983)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H341: Suspected of causing genetic defects
Warning Germ cell mutagenicity - Category 2 - H360: May damage fertility or the unborn child
Danger Reproductive toxicity - Category 1A, 1B - H371: May cause damage to organs
Warning Specific target organ toxicity, single exposure - Category 2 - H373: Causes damage to organs through prolonged or repeated exposure
Warning Specific target organ toxicity, repeated exposure - Category 2 -
SMILESCC1CCC(CC1)NC(=O)N(CCCl)N=O
-
InChIKeyFVLVBPDQNARYJU-UHFFFAOYSA-N
- Pubchem - semustine
- Wikipedia - semustine
Semustine is a drug used in chemotherapy. It is structurally similar to lomustine, being distinguished from it only by an additional methyl group. It has been taken off the drug market for investigation of its cancerous effects, rated as IARC Group 1 carcinogen or a known carcinogen.
Suppliers
Most-cited Publications
Safety
Alternate Names
External Links
Synthesis
Similar Compounds
Cyclamic acid
(100-88-9)
1 alternate name
3 suppliers
Chlorotoluron
(15545-48-9)
1 alternate name
3 safety hazards
3 suppliers
N,N-Bis(2-hydroxyethyl)dodecanamide
(120-40-1, 72968-36-6)
1 alternate name
3 suppliers
Menthyl acetate
(89-48-5, 20777-36-0, 29066-34-0, 16409-45-3, 2552-91-2, 2230-87-7, 2623-23-6)
1 alternate name
3 suppliers
1,3-Dicyclohexylthiourea
(1212-29-9)
1 alternate name
3 suppliers
p-MENTHAN-8-OL
(5114-00-1, 7322-63-6, 498-81-7, 29789-01-3)
1 alternate name
3 suppliers
p-Menthane hydroperoxide
(80-47-7)
1 alternate name
2 safety hazards
3 suppliers
alpha-TERPINEOL
(8000-41-7, 10482-56-1, 68797-63-7, 2438-12-2, 98-55-5)
1 alternate name
3 suppliers
minoxidil
(38304-91-5)
1 alternate name
3 suppliers
SIDURON
(1982-49-6)
1 alternate name
3 suppliers
(+)-alpha-Terpineol
(7785-53-7, 98-55-5)
1 alternate name
3 suppliers
(-)-alpha-Terpineol
(10482-56-1)
1 alternate name
3 suppliers
19438-60-9
(19438-60-9, 25550-51-0)
1 alternate name
2 safety hazards
3 suppliers
1,8-Diamino-p-menthane
(80-52-4, 26183-13-1)
1 alternate name
3 suppliers
2-chloro-N-(4-methylphenyl)acetamide
(16634-82-5)
1 alternate name
3 safety hazards
3 suppliers
Betamipron
(3440-28-6)
1 alternate name
3 suppliers
PEBULATE
(1114-71-2)
1 alternate name
1 safety hazard
3 suppliers
THIDIAZURON
(51707-55-2)
1 alternate name
3 suppliers
Hexahydrophthalic anhydride
(85-42-7, 14166-21-3)
1 alternate name
3 safety hazards
3 suppliers
2-ETHYLHEXYL METHACRYLATE
(688-84-6, 25719-51-1)
1 alternate name
3 safety hazards
3 suppliers
4-NITROSODIPHENYLAMINE
(86-30-6, 156-10-5)
1 alternate name
3 suppliers
Hippuric acid
(495-69-2)
1 alternate name
3 suppliers
N-Phenylmaleimide
(941-69-5)
1 alternate name
1 safety hazard
3 suppliers
Methylhexahydrophthalic anhydride
(48122-14-1, 19438-60-9, 25550-51-0)
1 alternate name
2 safety hazards
3 suppliers
Phenylacetylglycine
(500-98-1)
1 alternate name
3 suppliers
N-(2-HYDROXYETHYL)DODECANAMIDE
(68140-00-1, 142-78-9)
1 alternate name
3 suppliers
1-Monolaurin
(142-18-7, 27215-38-9, 67701-26-2)
1 alternate name
3 suppliers
N-(2-Furoyl)glycine
(5657-19-2)
1 alternate name
3 suppliers
CYCLOHEXANECARBOXYLIC ACID
(50825-29-1, 98-89-5)
1 alternate name
3 suppliers
3006-82-4
(3006-82-4)
1 alternate name
2 safety hazards
3 suppliers
CYCLOHEXYL ANTHRANILATE
(7779-16-0)
1 alternate name
3 suppliers
3,3-Tetramethyleneglutarimide
(1075-89-4)
1 alternate name
1 safety hazard
3 suppliers
CARVYL ACETATE
(97-42-7, 7053-79-4)
1 alternate name
3 suppliers
2-Chloroacetanilide
(587-65-5)
1 alternate name
3 suppliers
Cyclohexanol, 1,1'-dioxybis-
(2407-94-5)
1 alternate name
3 safety hazards
3 suppliers
2,4-Diisocyanatotoluene
(584-84-9, 86-91-9, 26006-20-2)
1 alternate name
5 safety hazards
3 suppliers
Dipentene
(7705-14-8, 9003-73-0, 8008-56-8, 65996-98-7, 8008-57-9, 138-86-3, 8028-38-4, 0008008-57-9)
1 alternate name
4 safety hazards
3 suppliers
D-Limonene
(5989-27-5, 68606-81-5, 5989-27-5, 65996-98-7)
1 alternate name
3 safety hazards
3 suppliers
2-CHLOROACETOPHENONE
(532-27-4)
1 alternate name
3 safety hazards
3 suppliers
2-ETHYLHEXANOIC ACID
(56006-48-5, 149-57-5, 125804-07-1, 61788-37-2)
1 alternate name
5 safety hazards
3 suppliers
N-NITROSODIPHENYLAMINE
(86-30-6)
1 alternate name
4 safety hazards
3 suppliers
Oxotremorine
(70-22-4)
1 alternate name
3 suppliers
d-Carvone
(2244-16-8)
1 alternate name
3 suppliers
(-)-Carvone
(6485-40-1)
1 alternate name
3 suppliers
2-ETHYLHEXYL ACRYLATE
(103-11-7, 9003-77-4)
1 alternate name
6 safety hazards
3 suppliers
CARVONE
(99-49-0, 8008-79-5)
1 alternate name
3 suppliers
Icaridin
(119515-38-7)
1 alternate name
3 suppliers
1,3-DICHLORO-5,5-DIMETHYLHYDANTOIN
(118-52-5)
1 alternate name
3 safety hazards
3 suppliers
VERNOLATE
(1929-77-7)
1 alternate name
3 safety hazards
3 suppliers
Cyclohexyl isocyanate
(3173-53-3)
1 alternate name
3 suppliers
DICYCLOHEXYLAMINE
(101-83-7)
1 alternate name
8 safety hazards
3 suppliers
DICYCLOHEXYLCARBODIIMIDE
(538-75-0)
1 alternate name
3 safety hazards
3 suppliers
CYCLOHEXANONE PEROXIDE
(78-18-2, 12262-58-7)
1 alternate name
3 safety hazards
3 suppliers
P-TOLUENESULFONAMIDE
(70-55-3)
1 alternate name
3 suppliers
Amylcinnamaldehyde
(1331-92-6, 78605-96-6, 122-40-7)
1 alternate name
2 safety hazards
3 suppliers
2-Benzylideneheptanal
(1331-92-6, 101365-33-7, 122-40-7)
1 alternate name
2 safety hazards
3 suppliers
85-40-5
(27813-21-4, 85-40-5)
1 alternate name
3 suppliers
2855-13-2
(2855-13-2)
1 alternate name
5 safety hazards
3 suppliers
122-40-7
(1331-92-6, 122-40-7)
1 alternate name
2 safety hazards
3 suppliers
2,3,5-Trimethacarb
(2655-15-4, 12407-86-2)
1 alternate name
3 suppliers
1-Butyl-1-nitrosourea
(869-01-2)
1 alternate name
3 suppliers
CARBROMAL
(77-65-6)
1 alternate name
3 suppliers
PHTHALAMIDE
(88-96-0)
1 alternate name
3 suppliers
2-(4-methylphenyl)propan-2-ol
(1197-01-9)
1 alternate name
3 suppliers
4-OCTYLPHENOL
(71902-25-5, 1806-26-4)
1 alternate name
2 safety hazards
3 suppliers
p-Menthane
(6069-98-3, 99-82-1, 1678-82-6)
1 alternate name
2 safety hazards
3 suppliers
(-)-Limonene
(5989-54-8)
1 alternate name
3 safety hazards
3 suppliers
gly-pro
(118203-80-8, 704-15-4)
1 alternate name
3 suppliers
3,3,5-TRIMETHYLCYCLOHEXANOL
(116-02-9, 933-48-2, 767-54-4)
1 alternate name
3 suppliers
p-Cymen-8-ol
(1197-01-9)
1 alternate name
3 suppliers
BARBITURIC ACID
(67-52-7, 4390-16-3)
1 alternate name
3 suppliers
Salicyluric acid
(487-54-7)
1 alternate name
3 suppliers
semustine
CAS Directory
