Cyclamic acid (100-88-9)

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Suppliers

• Sigma-Aldrich - Cyclamic acid
  166.50 - 330.75 USD
• Fisher Scientific - Search for Cyclamic acid
• TCI - Cyclamic acid
  32.00 - 249.00 USD

Most-cited Publications

• Bladder Tumors in Rats Fed Cyclohexylamine or High Doses of a Mixture of Cyclamate and Saccharin (Science, 1970)
• Evaluation of a new model to detect bladder carcinogens or co-carcinogens; results obtained with saccharin, cyclamate and cyclophosphamide (Chemico-Biological Interactions, 1975)
• Identification of the Cyclamate Interaction Site within the Transmembrane Domain of the Human Sweet Taste Receptor Subunit T1R3 (Journal of Biological Chemistry, 2005)
• Mutagenicity testing of cyclamate and some pesticides inDrosophila melanogaster (Cellular and Molecular Life Sciences, 1974)
• Measurement of the relative sweetness of stevia extract, aspartame and cyclamate/saccharin blend as compared to sucrose at different concentrations (Plant Foods for Human Nutrition, 1999)
• Cytogenetic studies in rats of cyclohexylamine, a metabolite of cyclamate. (Science, 1969)

Areas of Application

Safety

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Trends

Alternate Names

• Cyclamate
• Cyclamates
• Sodium Cyclamate
• Calcium Cyclamate
• Potassium Cyclamate
• Cyclamate, Calcium (2:1) Salt, Dihydrate
• Cyclamate, Sodium Salt
• Cyclamate Calcium (2:1) Salt
• SMILES
  C1CCC(CC1)NS(=O)(=O)O
• InChIKey
  HCAJEUSONLESMK-UHFFFAOYSA-N

External Links

• Pubchem - Cyclamic acid
• Wikipedia - cyclamic acid
  Cyclamic acid is a compound with formula C6H13NO3S. It is included in E number "E952". Cyclamic Acid is mainly used as catalyst in the production of paints and plastics, and furthermore as reagent for laboratories.

Synthesis

SULFAMIC ACID  +  CHLOROCYCLOHEXANE (Alkylation of primary amines)

CHLOROSULFONIC ACID  +  CYCLOHEXYLAMINE (Sulfonamide)

Cyclohexylboronic acid  +  CID 5475682 (Chan-Lam coupling reaction)

Synthesis of Cyclamic acid ›

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Cyclamic acid

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