| Weight | 267.245 g/mol |
|---|---|
| Formula | C10H13N5O4 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
2'-deoxyguanosine
Deoxyguanosine
116002-28-9, 38559-49-8, 961-07-9
Score:
#1369 in Biochemistry
,
#3308 in Biology
,
#4127 in Chemistry
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- TCI - 2'-deoxyguanosine43.00 - 468.00 USD
- Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine. (Proceedings of the National Academy of Sciences of the United States of America, 1990)
- Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. (Mutation Research-reviews in Mutation Research, 1997)
- Possible relevance of O-6 alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides. (Nature, 1969)
- Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents (Nucleic Acids Research, 1984)
- 8-hydroxy-2 -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis (Journal of Environmental Science and Health Part C-environmental Carcinogenesis & Ecotoxicology Reviews, 2009)
- Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage (Proceedings of the National Academy of Sciences of the United States of America, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Deoxyguanosine
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SMILESC1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)CO)O
-
InChIKeyYKBGVTZYEHREMT-UHFFFAOYSA-N
- Pubchem - 2'-deoxyguanosine
- Wikipedia - 2'-deoxyguanosine
Deoxyguanosine is composed of the purine nucleobase guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is similar to guanosine, but with one hydroxyl group removed from the 2' position of the ribose sugar (making it deoxyribose). If a phosphate group is attached at the 5' position, it becomes deoxyguanosine monophosphate.
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