| Weight | 197.234 g/mol |
|---|---|
| Formula | C10H15NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
Metanephrine (5001-33-2)
Score:
#1575 in Biochemistry
,
#3617 in Biology
,
#4542 in Chemistry
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- Sigma-Aldrich - Search for Metanephrine
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- A simple analysis for normetanephrine and metanephrine in urine (Clinica Chimica Acta, 1960)
- THE PHYSIOLOGICAL DISPOSITION OF H3-EPINEPHRINE AND ITS METABOLITE METANEPHRINE (Journal of Pharmacology and Experimental Therapeutics, 1959)
- Plasma Normetanephrine and Metanephrine for Detecting Pheochromocytoma in von HippelLindau Disease and Multiple Endocrine Neoplasia Type 2 (The New England Journal of Medicine, 1999)
- The Metabolic Fate of H3-Epinephrine and C14-Metanephrine in the Rat (Journal of Biological Chemistry, 1961)
- Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma. (Clinical Chemistry, 2011)
- Plasma Free Metanephrine Measurement Using Automated Online Solid-Phase Extraction HPLCTandem Mass Spectrometry (Clinical Chemistry, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCNCC(C1=CC(=C(C=C1)O)OC)O
-
InChIKeyJWJCTZKFYGDABJ-UHFFFAOYSA-N
- Pubchem - Metanephrine
- Wikipedia - metanephrine
Metanephrine (metadrenaline) is a metabolite of epinephrine (adrenaline) created by action of catechol-O-methyl transferase on epinephrine. An article in the Journal of the American Medical Association, 2002, indicated that the measurement of plasma free levels of the metanephrines group of molecules (including metanephrine and normetanephrine) is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm.
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Synthesis
Reactant
+
4-Chloro-2-methoxyphenol
(Grignard alcohol)
Methylboronic acid
+
Reactant
(Chan-Lam coupling reaction)
Reactant
+
Methyl hydroperoxide
(Dakin oxidation)
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