Weight | 208.257 g/mol |
---|---|
Formula | C12H16O3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 4 |
alpha-Asarone
asarone · trans-asarone · isoasarone
494-40-6, 2883-98-9, 5273-86-9
Score:
#954 in Biochemistry
,
#2522 in Biology
,
#3144 in Chemistry
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- Sigma-Aldrich - alpha-Asarone47.90 - 59.50 USD
- Fisher Scientific - Search for alpha-Asarone
- TCI - alpha-Asarone38.00 - 129.00 USD
- Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus (Life Sciences, 2002)
- Antioxidant property of -asarone against noise-stress-induced changes in different regions of rat brain (Pharmacological Research, 2005)
- Genotoxicity of the alkenylbenzenes and -asarone, myristicin and elemicin as determined by the UDS assay in cultured rat hepatocytes (Food and Chemical Toxicology, 1994)
- Neuroprotective effect of alpha-asarone on spatial memory and nitric oxide levels in rats injected with amyloid-(25-35). (Neuroscience Letters, 2009)
- Beta-Asarone Improves Cognitive Function by Suppressing Neuronal Apoptosis in the Beta-Amyloid Hippocampus Injection Rats (Biological & Pharmaceutical Bulletin, 2010)
- A Good Bargain: An Inexpensive, Air-Stable Ruthenium Metathesis Catalyst Derived from -Asarone (European Journal of Organic Chemistry, 2003)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - asarone
- trans-asarone
- isoasarone
- (E)-asarone
- benzene, 1,2,4-trimethoxy-5-(1E)-1-propen-1-yl-
- cis-isoelemicin
- asarone, (E)-isomer
- cis-isoasarone
- (Z)-asarone
- beta-asarone
- 1,2,4-trimethoxy-5-propenylbenzene, z-
- 2,4,5-trimethoxypropen-1-ylbenzene
- benzene, 1,2,4-trimethoxy-5-(1-propenyl)-, (Z)-
- gamma-asarone
- cis-beta-asarone
- benzene, 1,2,4-trimethoxy-5-(1-propenyl)-, (E)-
- asarone, (Z)-isomer
-
SMILESCC=CC1=CC(=C(C=C1OC)OC)OC
-
InChIKeyRKFAZBXYICVSKP-UHFFFAOYSA-N
- Pubchem - alpha-Asarone
- Wikipedia - -asarone
Asarone, which includes alpha (trans) and beta (cis) types, is an ether found in certain plants such as Acorus and Asarum. As a volatile fragrance oil, it is used in killing pests and bacteria. The toxicity and carcinogenicity of asarone means that it may be difficult to develop practical anthelmintics and insecticides based on it.
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Synthesis
Reactant
+
Methyl hydroperoxide
(Dakin oxidation)
Reactant
+
1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide
(Nicolaou IBX dehydrogenation)
PROPYLENE
+
Reactant
(Heck terminal vinyl)
1-Propenyl bromide
+
Reactant
(Stille)
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