| Weight | 162.188 g/mol |
|---|---|
| Formula | C10H10O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
safrole (94-59-7)
Safrol · 4 Allyl 1,2 methylenedioxybenzene · 4-Allyl-1,2-methylenedioxybenzenes
Score:
#250 in Biochemistry
,
#947 in Biology
,
#1047 in Chemistry
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- Structure-Activity Studies of the Carcinogenicities in the Mouse and Rat of Some Naturally Occurring and Synthetic Alkenylbenzene Derivatives Related to Safrole and Estragole (Cancer Research, 1983)
- The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo (Cancer Letters, 1993)
- Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole (Carcinogenesis, 1994)
- 32P-Post-labelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. II. Newborn male B6C3F1 mice (Carcinogenesis, 1984)
- The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole. (British Journal of Cancer, 1983)
- SYNTHESIS AND ANALGESIC ACTIVITY OF NOVEL N-ACYLARYLHYDRAZONES AND ISOSTERS, DERIVED FROM NATURAL SAFROLE (European Journal of Medicinal Chemistry, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H350: May cause cancer
Danger Carcinogenicity - Category 1A, 1B - H351: Suspected of causing cancer
Warning Carcinogenicity - Category 2 - H373: Causes damage to organs through prolonged or repeated exposure
Warning Specific target organ toxicity, repeated exposure - Category 2 - Safrol
- 4 Allyl 1,2 methylenedioxybenzene
- 4-Allyl-1,2-methylenedioxybenzenes
- 4-Allyl-1,2-methylenedioxybenzene
- Safroles
- Shikimol
- Shikimols
- Safrols
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SMILESC=CCC1=CC2=C(C=C1)OCO2
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InChIKeyZMQAAUBTXCXRIC-UHFFFAOYSA-N
- Pubchem - safrole
- Wikipedia - safrole
Safrole is a phenylpropene. It is a colorless or slightly yellow oily liquid typically extracted from the root-bark or the fruit of sassafras plants in the form of sassafras oil (although commercially available culinary sassafras oil is usually devoid of safrole due to a rule passed by the FDA in 1960), or is synthesized from catechol or other related methylenedioxy compounds. It is the principal component of brown camphor oil, and is found in small amounts in a wide variety of plants, where it functions as a natural pesticide.
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safrole
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