trans-Anethole

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Suppliers

• Sigma-Aldrich - trans-Anethole
  28.40 - 770.00 USD
• Fisher Scientific - Search for trans-Anethole
• TCI - trans-Anethole
  21.00 - 131.00 USD

Most-cited Publications

• Inhibition of foodborne pathogens by thymol, eugenol, menthol and anethole (International Journal of Food Microbiology, 1987)
• Anethole blocks both early and late cellular responses transduced by tumor necrosis factor : effect on NF-B, AP-1, JNK, MAPKK and apoptosis (Oncogene, 2000)
• A Randomized Phase IIb Trial of Anethole Dithiolethione in Smokers with Bronchial Dysplasia (Journal of the National Cancer Institute, 2002)
• The mutagenicities of safrole, estragole, eugenol, trans-anethole, and some of their known or possible metabolites for Salmonella typhimurium mutants. (Mutation Research, 1979)
• Tacrine-induced Reactive Oxygen Species in a Human Liver Cell Line: The Role of Anethole Dithiolethione as a Scavenger. (Toxicology in Vitro, 1999)
• Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. (Pharmacological Research, 2007)

Areas of Application

Safety

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Trends

Alternate Names

• anethole
• 1-methoxy-4-(1-propenyl)benzene
• p-propenylanisole
• 1-(4-methoxyphenyl)propene
• anethole, (Z)-isomer
• anethole, (E)-isomer
• SMILES
  CC=CC1=CC=C(C=C1)OC
• InChIKey
  RUVINXPYWBROJD-UHFFFAOYSA-N

External Links

• Pubchem - trans-Anethole
• Wikipedia - anethole
  Anethole (anise camphor) is an organic compound that is widely used as a flavoring substance. It is a derivative of phenylpropene, a type of aromatic compound that occurs widely in nature, in essential oils. It contributes a large component of the odor and flavor of anise and fennel (both in the botanical family Apiaceae), anise myrtle (Myrtaceae), liquorice (Fabaceae), camphor, magnolia blossoms, and star anise (Illiciaceae).

Synthesis

acetaldehyde  +  4-Methoxybenzyl chloride (Wittig)

PROPYLENE  +  4-Chloroanisole (Heck terminal vinyl)

1-Propenyl bromide  +  4-Chloroanisole (Stille)

Reactant  +  Methyl hydroperoxide (Dakin oxidation)

Reactant  +  1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide (Nicolaou IBX dehydrogenation)

Synthesis of trans-Anethole ›

Similar Compounds

cis-Anethole (4180-23-8, 25679-28-1, 104-46-1)

7 alternate names

3 suppliers

p-Propenylanisole (50770-19-9, 104-46-1)

7 alternate names

3 suppliers

Anisole, p-propenyl- (104-46-1, 50770-19-9)

7 alternate names

3 suppliers

4-Vinylphenol (2628-17-3)

7 alternate names

3 suppliers

Isoeugenol (5932-68-3, 97-54-1)

7 alternate names

4 safety hazards

3 suppliers

ISOSAFROLE (4043-71-4, 120-58-1)

7 alternate names

3 suppliers

alpha-Isosafrole (17627-76-8, 120-58-1)

7 alternate names

3 suppliers

120-58-1 (120-58-1)

7 alternate names

3 suppliers

1,4-DIETHYLBENZENE (10565-77-2, 105-05-5)

7 alternate names

3 safety hazards

3 suppliers

4'-Methoxyacetophenone (100-06-1)

7 alternate names

3 suppliers

1,4-Dimethoxybenzene (150-78-7)

7 alternate names

3 suppliers

4-ETHYLPHENOL (123-07-9, 29471-88-3)

7 alternate names

1 safety hazard

3 suppliers

4-Methylanisole (104-93-8, 3494-45-9)

7 alternate names

3 suppliers

4-Chlorostyrene (1073-67-2)

7 alternate names

3 suppliers

4-Isopropylphenol (99-89-8)

7 alternate names

3 suppliers

P-XYLENE (68650-36-2, 68411-39-2, 106-42-3)

7 alternate names

5 safety hazards

3 suppliers

Divinylbenzene (61804-50-0, 91-14-5, 1321-74-0, 9003-69-4)

7 alternate names

1 safety hazard

3 suppliers

5-Ethyl-2-methylpyridine (104-90-5)

7 alternate names

5 safety hazards

3 suppliers

Dihydrosafrole (94-58-6)

7 alternate names

2 safety hazards

3 suppliers

1-Phenoxy-2-propanol (770-35-4)

7 alternate names

1 safety hazard

3 suppliers

4-(Methylamino)phenol (150-75-4)

7 alternate names

3 suppliers

beta-Methylstyrene (637-50-3, 873-66-5)

7 alternate names

3 suppliers

4-ETHOXYANILINE (156-43-4)

7 alternate names

8 safety hazards

3 suppliers

4'-Hydroxyacetophenone (99-93-4)

7 alternate names

3 suppliers

cis-Methylisoeugenol (6379-72-2, 6380-24-1, 93-16-3)

7 alternate names

3 suppliers

4-isopropylbenzyl alcohol (536-60-7)

7 alternate names

3 suppliers

2-PROPYLPHENOL (644-35-9, 31019-46-2)

7 alternate names

3 suppliers

Methylisoeugenol (6379-72-2, 54349-79-0, 93-16-3)

7 alternate names

3 suppliers

Benzaldehyde dimethyl acetal (1125-88-8)

7 alternate names

3 suppliers

4-Methoxybenzyl acetate (1331-83-5, 104-21-2)

7 alternate names

3 suppliers

2-METHOXY-4-PROPYLPHENOL (2785-87-7)

7 alternate names

3 suppliers

STYRENE (9003-53-6, 100-42-5, 98444-30-5, 12770-88-6, 68441-35-0)

7 alternate names

10 safety hazards

3 suppliers

p-Toluidine (26915-12-8, 106-49-0)

7 alternate names

8 safety hazards

3 suppliers

safrole (94-59-7)

7 alternate names

4 safety hazards

3 suppliers

2,4-DIMETHYLPHENOL (105-67-9)

7 alternate names

6 safety hazards

3 suppliers

Methyl 4-hydroxybenzoate (99-76-3)

7 alternate names

1 safety hazard

3 suppliers

p-Anisidine (104-94-9, 29191-52-4)

7 alternate names

3 safety hazards

3 suppliers

CUMENE HYDROPEROXIDE (80-15-9)

7 alternate names

9 safety hazards

3 suppliers

Propylbenzene (103-65-1)

7 alternate names

3 safety hazards

3 suppliers

Butylbenzene (104-51-8)

7 alternate names

2 safety hazards

3 suppliers

4-Chlorotoluene (3327-51-3, 106-43-4)

7 alternate names

5 safety hazards

3 suppliers

4-(4-Hydroxyphenyl)-2-butanone (5471-51-2)

7 alternate names

3 suppliers

4-Methylstyrene (622-97-9, 1319-73-9, 24936-41-2)

7 alternate names

3 suppliers

99-98-9 (99-98-9)

7 alternate names

2 safety hazards

3 suppliers

1,2-DIETHYLBENZENE (25340-17-4, 1321-74-0, 135-01-3)

7 alternate names

2 safety hazards

3 suppliers

1,3-DIETHYLBENZENE (68584-01-0, 141-93-5)

7 alternate names

2 safety hazards

3 suppliers

2-Chlorostyrene (2039-87-4)

7 alternate names

2 safety hazards

3 suppliers

4-Methylbenzyl alcohol (589-18-4, 31831-37-5)

7 alternate names

3 suppliers

4'-Chloroacetophenone (99-91-2)

7 alternate names

1 safety hazard

3 suppliers

N-Ethyl-m-toluidine (102-27-2)

7 alternate names

2 safety hazards

3 suppliers

2-ETHYLPHENOL (90-00-6, 25429-37-2)

7 alternate names

1 safety hazard

3 suppliers

2-Phenyl-2-propanol (617-94-7)

7 alternate names

3 suppliers

4-BROMOTOLUENE (106-38-7)

7 alternate names

3 suppliers

3-ETHYLPHENOL (620-17-7)

7 alternate names

1 safety hazard

3 suppliers

4'-Aminoacetophenone (99-92-3)

7 alternate names

3 suppliers

1-Phenylethanamine (98-84-0, 618-36-0)

7 alternate names

4 safety hazards

3 suppliers

p-Toluenethiol (26445-03-4, 106-45-6)

7 alternate names

3 suppliers

2-Isopropylphenol (88-69-7, 25168-06-3)

7 alternate names

3 suppliers

3-Chlorostyrene (2039-85-2)

7 alternate names

3 suppliers

1-Ethyl-2-methylbenzene (25550-14-5, 611-14-3 (2-ethyl toluene), 611-14-3)

7 alternate names

3 suppliers

4-isopropylbenzaldehyde (122-03-2)

7 alternate names

1 safety hazard

3 suppliers

1,2-Dimethoxybenzene (91-16-7)

7 alternate names

1 safety hazard

3 suppliers

alpha-Methyl cinnamaldehyde (101-39-3, 66051-14-7)

7 alternate names

3 suppliers

ALPHA-METHYLCINNAMALDEHYDE (101-39-3, 15174-47-7)

7 alternate names

3 suppliers

1-Phenylethanethiol (6263-65-6)

7 alternate names

3 suppliers

1,3-Dimethoxybenzene (151-10-0)

7 alternate names

1 safety hazard

3 suppliers

Hordenine (62493-39-4, 3595-05-9, 539-15-1)

7 alternate names

3 suppliers

4-Fluorotoluene (352-32-9)

7 alternate names

3 suppliers

4-Ethyl-2-methoxyphenol (2785-89-9)

7 alternate names

3 suppliers

4-Methylbenzyl chloride (104-82-5, 57030-73-6)

7 alternate names

1 safety hazard

3 suppliers

4-METHOXYBENZYL ALCOHOL (1331-81-3, 105-13-5)

7 alternate names

3 suppliers

4-ETHYLBENZALDEHYDE (4748-78-1)

7 alternate names

3 suppliers

3-(Ethylamino)phenol (621-31-8)

7 alternate names

3 suppliers

ALPHA-METHYLCINNAMALDEHYDE (101-39-3)

7 alternate names

3 suppliers

m-Xylene (68908-87-2, 108-38-3)

7 alternate names

6 safety hazards

3 suppliers

CHLOROBENZENE (50717-45-8, 108-90-7, 68411-45-0)

7 alternate names

3 safety hazards

3 suppliers

o-Xylene (95-47-6, 68411-84-7)

7 alternate names

5 safety hazards

3 suppliers

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trans-Anethole

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