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Weight196.202 g/mol
FormulaC10H12O4
Hydrogen Acceptors4
Hydrogen Donors3
Aromatic Rings1
Rotatable Bonds3

Thbp (1421-63-2)

tetrahydrobiopterin  ·  BPH4  ·  5,6,7,8-tetrahydrobiopterin

Score: #820 in Neuroscience , #1571 in Biochemistry , #3610 in Biology , #4532 in Chemistry
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Alternate Names

  • tetrahydrobiopterin
  • BPH4
  • 5,6,7,8-tetrahydrobiopterin
  • tetrahydro-6-biopterin
  • 5,6,7,8-tetrahydrodictyopterin
  • 1-butanone, 1-(2,4,5-trihydroxyphenyl)
  • phenylalanine hydroxylase cofactor
  • 5,6,7,8-tetrahydrobiopterin, (S-(R*,S*))-isomer
  • sapropterin dihydrochloride
  • 5,6,7,8-erythro-tetrahydrobiopterin
  • 2,4,5-trihydroxybutyrophenone
  • 5,6,7,8-tetrahydro-L-erythrobiopterin
  • 6R-L-erythro-5,6,7,8-tetrahydrobiopterin
  • kuvan
  • 6R-BH4
  • D-threo-tetrahydrobiopterin
  • sapropterin
  • trihydroxybutyrophenone
  • 2',4',5'-trihydroxybutyrophenone
  • SMILES
    CCCC(=O)C1=CC(=C(C=C1O)O)O
  • InChIKey
    SRUQARLMFOLRDN-UHFFFAOYSA-N

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Synthesis

Butyronitrile  +  5-chlorobenzene-1,2,4-triol (Grignard carbonyl)
1,2,4-BENZENETRIOL  +  Butyryl chloride (Friedel-Crafts acylation)
Reactant  +  dimethyl sulfide (Corey-Kim oxidation of secondary alcohols)
Synthesis of Thbp ›

Similar Compounds

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480-66-0 (480-66-0)
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