Weight | 179.219 g/mol |
---|---|
Formula | C10H13NO2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
2-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (37491-98-8, 63937-92-8)
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- Sigma-Aldrich - Search for 2-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
- Fisher Scientific - Search for 2-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
- TCI - Search for 2-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
- Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies (Brain Research, 1996)
- Presence of 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, novel endogenous amines, in parkinsonian and normal human brains (Biochemical and Biophysical Research Communications, 1991)
- 1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol) is toxic to dopaminergic neuroblastoma SH-SY5Y cells via impairment of cellular energy metabolism. (Brain Research, 2000)
- A dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl(R)salsolinol, and its oxidation product, 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion, accumulate in the nigro-striatal system of the human brain (Neuroscience Letters, 1997)
- Inhibition of Tyrosine Hydroxylase by R and S Enantiomers of Salsolinol, 1-Methyl-6,7-Dihydroxy-1,2,3,4- Tetrahydroisoquinoline (Journal of Neurochemistry, 1992)
- Studies on the neurotoxicity of 6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline (salsolinol) in SH-SY5Y cells (European Journal of Pharmacology: Environmental Toxicology and Pharmacology, 1995)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN1CCC2=CC(=C(C=C2C1)O)O
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InChIKeyWETXYFNVBDLWIW-UHFFFAOYSA-N
- Pubchem - 2-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
- Wikipedia - 2(N)-Methyl-norsalsolinol
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