Weight | 84.118 g/mol |
---|---|
Formula | C5H8O |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
3,4-Dihydro-2H-pyran (25512-65-6, 110-87-2)
3,4-dihydropyran
Score:
#1407 in Biochemistry
,
#4192 in Chemistry
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- Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor. (Journal of Medicinal Chemistry, 2009)
- THE MECHANISMS OF THE HALOGENATIONS AND HALOGENOMETHOXYLATIONS OF D-GLUCAL TRIACETATE, D-GALACTAL TRIACETATE, AND 3,4-DIHYDROPYRAN (Canadian Journal of Chemistry, 1965)
- Organocatalytic Asymmetric Synthesis of Functionalized 3,4-Dihydropyran Derivatives (Chemistry: A European Journal, 2008)
- The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents (Neuropharmacology, 2011)
- Potentiation of Halogenated Pyrimidine Radiosensitizers in Human Carcinoma Cells by -Lapachone (3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione), a Novel DNA Repair Inhibitor (Cancer Research, 1987)
- A nitrile oxide based entry to 2,3-dihydropyran-4-ones: synthesis of a protected version of compactin lacton in racemic and optically active forms (Journal of Organic Chemistry, 1985)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H225: Highly Flammable liquid and vapor
Danger Flammable liquids - Category 2 - 3,4-dihydropyran
-
SMILESC1CC=COC1
-
InChIKeyBUDQDWGNQVEFAC-UHFFFAOYSA-N
- Pubchem - 3,4-Dihydro-2H-pyran
- Wikipedia - 3,4-dihydro-2H-pyran
Dihydropyran is a heterocyclic compound with the formula C5H8O. The six-membered, non-aromatic ring has five carbon atoms and one oxygen atom. It contains one double bond.
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Synthesis
Reactant
+
1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide
(Nicolaou IBX dehydrogenation)
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3,6-Dihydro-2H-pyran
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3,4-Dihydro-2H-pyran-2-carbaldehyde
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4-Hexen-1-ol, (4Z)-
(928-91-6, 6126-50-7)
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(110-45-2)
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(14320-38-8)
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4-PENTEN-2-OL
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(6338-52-9)
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(16698-52-5)
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57883-06-4
(57883-06-4)
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(926-66-9)
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(9035-85-2)
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(112-34-5)
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1,4-Diacetoxybutane
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