| Weight | 98.101 g/mol |
|---|---|
| Formula | C5H6O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
5,6-Dihydro-2H-pyran-2-one (3393-45-1)
Score:
#2958 in Biochemistry
,
#7240 in Chemistry
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- The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents (Neuropharmacology, 2011)
- Design and Discovery of 6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (PF-04447943), a Selective Brain Penetrant PDE9A Inhibitor for the Treatment of Cognitive Disorders (Journal of Medicinal Chemistry, 2012)
- The first stereoselective total synthesis of (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one (Tetrahedron Letters, 2004)
- Synthesis of polyhydroxyindolizidines from 5,6-dihydro-2H-pyran-2-one. (Carbohydrate Research, 2001)
- Stereoselective total synthesis of (+)-strictifolione and (6R)-6-[(4R,6R)-4,6-dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran-2-one by Prins reaction and olefin cross-metathesis (Tetrahedron-asymmetry, 2009)
- Structural Reassignment, Absolute Configuration, and Conformation of Hypurticin, a Highly Flexible Polyacyloxy-6-heptenyl-5,6-dihydro-2H-pyran-2-one (Journal of Natural Products, 2009)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1COC(=O)C=C1
-
InChIKeyQBDAFARLDLCWAT-UHFFFAOYSA-N
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