Weight | 119.12 g/mol |
---|---|
Formula | C4H9NO3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 3 |
Aromatic Rings | 0 |
Rotatable Bonds | 3 |
4-Amino-3-hydroxybutanoic acid (924-49-2, 352-21-6)
GABOB · 4-amino-3-hydroxybutyric acid, (Z)-2-butenedioate salt (2:1), (+-)-isomer · 4-amino-3-hydroxybutyric acid, hydrochloride
Score:
#1028 in Neuroscience
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- Sigma-Aldrich - 4-Amino-3-hydroxybutanoic acid95.70 USD
- Fisher Scientific - Search for 4-Amino-3-hydroxybutanoic acid
- TCI - 4-Amino-3-hydroxybutanoic acid44.00 - 133.00 USD
- Total synthesis of (R)-glycerol acetonide and the antiepileptic and hypotensive drug (-)-gamma-amino-beta-hydroxybutyric acid (GABOB): use of vitamin C as a chiral starting material (Journal of the American Chemical Society, 1980)
- Asymmetric epoxidation of homoallylic alcohols. Synthesis of (-)--amino-(R)-hydroxybutyric acid (GABOB) (Journal of Organic Chemistry, 1984)
- Short and practical syntheses of(R)-()-carnitine and (R)-()--amino--hydroxybutyric acid (GABOB) (Tetrahedron-asymmetry, 1993)
- Enantioselective Enzymatic Aminolysis and Ammonolysis of Dimethyl 3-Hydroxyglutarate. Synthesis of (R)-4-Amino-3-hydroxybutanoic Acid (Journal of Organic Chemistry, 1996)
- Practical synthesis of (R)--amino--hydroxybutanoic acid (GABOB) from (R)-epichlorohydrin (Tetrahedron Letters, 1987)
- Simple Three-Step Synthesis of (R)- and (S)-4-Amino-3-hydroxybutanoic Acid (GABOB) by Stereoselective Aldol Addition (Synthesis, 1989)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - GABOB
- 4-amino-3-hydroxybutyric acid, (Z)-2-butenedioate salt (2:1), (+-)-isomer
- 4-amino-3-hydroxybutyric acid, hydrochloride
- 4-amino-3-hydroxybutyric acid, (+-)-isomer
- 4-amino-3-hydroxybutyric acid, (Z)-2-butenedioate salt (1:1), (+-)-isomer
- 4-amino-3-hydroxybutyric acid, monosodium salt
- 4-amino-3-hydroxybutyric acid, (S)-isomer
- 4-amino-3-hydroxybutyric acid, ion (1-), (+-)-isomer
- gamma-amino-beta-hydroxybutyric acid
- 4-amino-3-hydroxybutyric acid, hydrobromide, magnesium salt
- 4-amino-3-hydroxybutyric acid
- 4-amino-3-hydroxybutyric acid, (R)-isomer
-
SMILESC(C(CN)O)C(=O)O
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InChIKeyYQGDEPYYFWUPGO-UHFFFAOYSA-N
- Pubchem - 4-Amino-3-hydroxybutanoic acid
- Wikipedia - -amino--hydroxybutyric acid
-Amino--hydroxybutyric acid (GABOB), also known as -hydroxy--aminobutyric acid (-hydroxy-GABA), and sold under the brand name Gamibetal among others, is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico. It is a GABA analogue, or an analogue of the neurotransmitter -aminobutyric acid (GABA), and has been found to be an endogenous metabolite of GABA.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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