Weight | 134.182 g/mol |
---|---|
Formula | C8H10N2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
5,6,7,8-tetrahydro-1,6-naphthyridine (80957-68-2)
80957-68-2
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- Methods for the synthesis of 5,6,7,8-tetrahydro-1,8-naphthyridine fragments for V3 integrin antagonists (Journal of Organic Chemistry, 2004)
- ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with Calcium Promotor and Neuroprotective Properties (Journal of Pharmacology and Experimental Therapeutics, 2004)
- Ready access to 7,8-dihydro- and 1,2,3,4-tetrahydro-1,6-naphthyridine-5(6H)-ones from simple pyridine precursors (Journal of Heterocyclic Chemistry, 2006)
- Antivertigo Agents. III. Synthesis of 5, 6, 7, 8-Tetrahydro-1, 6-naphthyridine Methyl Homologs (Chemical & Pharmaceutical Bulletin, 1984)
- A FACILE SYNTHESIS OF THE 3-AMINO-5,6,7,8-TETRAHYDRO[1,6]NAPHTHYRIDINE SYSTEM AND SOME ALKYLATED AND POLYCYCLIC HOMOLOGUES (Synthetic Communications, 2001)
- New heterocyclic systems based on 1-hydrazino-5,6,7,8-tetrahydro[2,7]naphthyridine: 7,8,9,10-tetra-hydro[1,2,4]triazolo[3,4-a]- and 7,8,9,10-tetra-hydro[1,2,4]triazolo[5,1-a][2,7]naphthyridines (Chemistry of Heterocyclic Compounds, 2012)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 80957-68-2
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SMILESC1CNCC2=C1N=CC=C2
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InChIKeyFPEAARFNXIWCTP-UHFFFAOYSA-N
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Most-cited Publications
Safety
Alternate Names
Estimated Properties
Boiling Point | 241.58 C | EPA T.E.S.T. |
---|---|---|
Boiling Point | 241.14 C | EPI Suite |
Density | 1.07 g/cm3 | EPA T.E.S.T. |
Flash Point | 103.08 C | EPA T.E.S.T. |
Melting Point | 55.59 C | EPI Suite |
Water Solubility | 28351.2 mg/L | EPA T.E.S.T. |
Water Solubility | 1e+06 mg/L | EPI Suite |
External Links
Synthesis
Reactant
+
3-(Aminomethyl)pyridine
(Reductive amination)
2-(2-Aminoethyl)pyridine
+
Reactant
(Alkylation of primary amines)
Reactant
+
CID 5477082
(Chan-Lam coupling reaction)
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