| Weight | 349.518 g/mol |
|---|---|
| Formula | C24H31NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
Abiraterone (154229-19-3)
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- Abiraterone and Increased Survival in Metastatic Prostate Cancer (The New England Journal of Medicine, 2011)
- Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy (The New England Journal of Medicine, 2013)
- AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer (The New England Journal of Medicine, 2014)
- Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven (Journal of Clinical Oncology, 2008)
- Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study (Lancet Oncology, 2012)
- Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer (Journal of Clinical Oncology, 2009)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC12CCC(CC1=CCC3C2CCC4(C3CC=C4C5=CN=CC=C5)C)O
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InChIKeyGZOSMCIZMLWJML-UHFFFAOYSA-N
- Pubchem - Abiraterone
- Wikipedia - abiraterone
Abiraterone, developmental code name CB-7598, also known as 17-(3-pyridyl)androsta-5,16-dien-3-ol, is a synthetic, steroidal CYP17A1 inhibitor. It is the active metabolite of abiraterone acetate, an ester and prodrug of abiraterone. A metabolite of abiraterone has been found to act as an agonist of the androgen receptor, and may antagonize the clinical effectiveness of abiraterone acetate.
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Abiraterone
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