| Weight | 416.526 g/mol |
|---|---|
| Formula | C21H32N6O3 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 9 |
ALFENTANIL (71195-58-9)
Score:
#389 in Neuroscience
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#1761 in Biology
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#2082 in Chemistry
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- Bispectral Analysis Measures Sedation and Memory Effects of Propofol, Midazolam, Isoflurane, and Alfentanil in Healthy Volunteers (Anesthesiology, 1997)
- Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil and nitrous oxide anesthesia (Anesthesiology, 1997)
- EEG quantitation of narcotic effect: the comparative pharmacodynamics of fentanyl and alfentanil. (Anesthesiology, 1985)
- Decreased fentanyl and alfentanil dose requirements with age. A simultaneous pharmacokinetic and pharmacodynamic evaluation. (Journal of Pharmacology and Experimental Therapeutics, 1987)
- Remifentanil versus alfentanil : Comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers (Anesthesiology, 1996)
- Measured Context-sensitive Half-times of Remifentanil and Alfentanil (Anesthesiology, 1995)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCN3C(=O)N(N=N3)CC)COC
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InChIKeyIDBPHNDTYPBSNI-UHFFFAOYSA-N
- Pubchem - ALFENTANIL
- Wikipedia - alfentanil
Alfentanil (R-39209, trade name Alfenta, Rapifen in Australia) is a potent but short-acting synthetic opioid analgesic drug, used for anaesthesia in surgery. It is an analogue of fentanyl with around 1/4 to 1/10 the potency of fentanyl and around 1/3 of the duration of action, but with an onset of effects 4x faster than fentanyl. Alfentanil has a pKa of approximately 6.5, which leads to a very high proportion of the drug being uncharged at physiologic pH.
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