| Weight | 270.163 g/mol |
|---|---|
| Formula | C12H13Cl2N3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
Alinidine (33178-86-8)
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- Pacemaker selectivity: influence on rabbit atria of ionic environment and of alinidine, a possible anion antagonist (Cardiovascular Research, 1981)
- Effects of alinidine, a novel bradycardic agent, on heart rate and blood pressure in man. (Journal of Cardiovascular Pharmacology, 1982)
- Improvement of perfusion and function of ischaemic porcine myocardium after reduction of heart rate by alinidine. (Journal of Cardiovascular Pharmacology, 1981)
- Alinidine modifies the pacemaker current in sheep Purkinje fibers (Pflgers Archiv: European Journal of Physiology, 1987)
- Haemodynamic and electrophysiologic actions of alinidine in the dog. (Archives internationales de pharmacodynamie et de thrapie, 1980)
- Electrophysiological study of alinidine in voltage clamped rabbit sino-atrial node cells (European Journal of Pharmacology, 1986)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC=CCN(C1=C(C=CC=C1Cl)Cl)C2=NCCN2
-
InChIKeyOXTYVEUAQHPPMV-UHFFFAOYSA-N
- Pubchem - Alinidine
- Wikipedia - alinidine
Alinidine (ST567) is a negative chronotrope that was developed in the 1970s and 1980s. It causes bradycardia by inhibiting the pacemaker current by altering the maximal channel conductance and alter the voltage threshold. The development of alinidine was halted because it was not sufficiently specific for its target.
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