| Weight | 74.087 g/mol |
|---|---|
| Formula | CH6N4 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
aminoguanidine (79-17-4)
pimagedine hydrochloride · hydrazinecarboximidamide · aminoguanidine sulfate
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#920 in Neuroscience
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#1886 in Biochemistry
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#4044 in Biology
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#5095 in Chemistry
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- Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking (Science, 1986)
- Selective inhibition of the inducible nitric oxide synthase by aminoguanidine (European Journal of Pharmacology, 1993)
- Aminoguanidine, a Novel Inhibitor of Nitric Oxide Formation, Prevents Diabetic Vascular Dysfunction (Diabetes, 1992)
- Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy (Proceedings of the National Academy of Sciences of the United States of America, 1991)
- Retardation by Aminoguanidine of Development of Albuminuria, Mesangial Expansion, and Tissue Fluorescence in Streptozocin-Induced Diabetic Rat (Diabetes, 1991)
- Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts. (Archives of Biochemistry and Biophysics, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - pimagedine hydrochloride
- hydrazinecarboximidamide
- aminoguanidine sulfate
- pimagedine
- monoaminoguanidine
-
SMILESC(=NN)(N)N
-
InChIKeyHAMNKKUPIHEESI-UHFFFAOYSA-N
- Pubchem - aminoguanidine
- Wikipedia - pimagedine
Pimagedine, also known as aminoguanidine, is an investigational drug for the treatment of diabetic nephropathy that is no longer under development as a drug. Pimagedine is a diamine oxidase and nitric oxide synthase inhibitor. It acts to reduce levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone.
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