| Weight | 408.882 g/mol |
|---|---|
| Formula | C20H25ClN2O5 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 8 |
amlodipine (88150-42-9)
Norvasc · Amlodipine Besylate · Istin
Score:
#87 in Biochemistry
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#396 in Biology
,
#413 in Chemistry
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- Sigma-Aldrich - Search for amlodipine
- Fisher Scientific - Search for amlodipine
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- Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. (The Lancet, 2005)
- Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial (The Lancet, 2004)
- Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension in High-Risk Patients (The New England Journal of Medicine, 2008)
- Effect of Amlodipine on Morbidity and Mortality in Severe Chronic Heart Failure (The New England Journal of Medicine, 1996)
- Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: A Randomized Controlled Trial (JAMA, 2001)
- Outcome Results of the Fosinopril Versus Amlodipine Cardiovascular Events Randomized Trial (FACET) in Patients With Hypertension and NIDDM (Diabetes Care, 1998)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H301: Toxic if swallowed
Danger Acute toxicity, oral - Category 3 - H373: Causes damage to organs through prolonged or repeated exposure
Warning Specific target organ toxicity, repeated exposure - Category 2 - H410: Very toxic to aquatic life with long lasting effects
Warning Hazardous to the aquatic environment, long-term hazard - Category 1 - Norvasc
- Amlodipine Besylate
- Istin
- Amlodipine Maleate (1:1)
- Amlor
- Amlodis
- Amlodipine, (R)-Isomer
- Almirall Brand of Amlodipine Besilate
- Astudal
- Amlodipine, (S)-Isomer, Maleate (1:1)
- Amlodipine, (+-)-Isomer
- Eczacibasi Brand of Amlodipine besilate
- Mack Brand of Amlodipine Besilate
- Amlodipine, (+-)-Isomer, Maleate (1:1)
- Amlodipine Maleate
- Pfizer Brand of Amlodipine Besilate
-
SMILESCCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
-
InChIKeyHTIQEAQVCYTUBX-UHFFFAOYSA-N
- Pubchem - amlodipine
- Wikipedia - amlodipine
Amlodipine, sold under the brand name Norvasc among others, is a medication used to treat high blood pressure and coronary artery disease. While not typically recommended in heart failure, amlodipine may be used if other medications are not sufficient for high blood pressure or heart related chest pain. Amlodipine is taken by mouth and has an effect for at least a day.
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Estimated Properties
| Boiling Point | 414.23 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.27 g/cm3 | EPA T.E.S.T. |
| Flash Point | 273.95 C | EPA T.E.S.T. |
| Water Solubility | 179.46 mg/L | EPA T.E.S.T. |
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