Weight | 334.331 g/mol |
---|---|
Formula | C17H29Cl2NO |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 5 |
Sibutramine hydrochloride monohydrate (125494-59-9)
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- Sibutramine hydrochloride monohydrate (Journal of Thermal Analysis and Calorimetry, 2010)
- Validation of an Analytical Method for Determination of Sibutramine Hydrochloride Monohydrate in Capsules by Uv-Vis Spectrophotometry (2007)
- Use of sibutramine hydrochloride monohydrate in the treatment of the painful peripheral neuropathy of diabetes. (Diabetes Care, 2000)
- Treatment of fibromyalgia with sibutramine hydrochloride monohydrate: comment on the article by Goldenberg et al. (Arthritis & Rheumatism, 2002)
- Development and validation of sensitive methods for determination of sibutramine hydrochloride monohydrate and direct enantiomeric separation on a protein-based chiral stationary phase. (Journal of AOAC International, 2008)
- Comparative Study on Dissolution Profiles of Sibutramine Hydrochloride Monohydrate from Commercial Capsules (Latin American Journal of Pharmacy, 2009)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C.O.Cl
-
InChIKeyKFNNPQDSPLWLCX-UHFFFAOYSA-N
- Pubchem - Sibutramine hydrochloride monohydrate
- Wikipedia - sibutramine hydrochloride
Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. Until 2010, it was widely marketed and prescribed as an adjunct in the treatment of obesity along with diet and exercise. It has been associated with increased cardiovascular events and strokes and has been withdrawn from the market in several countries and regions including Australia, Canada, China, the European Union, Hong Kong, India, Mexico, New Zealand, the Philippines, Thailand, the United Kingdom, and the United States.
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