| Weight | 269.772 g/mol |
|---|---|
| Formula | C14H20ClNO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
METHYLPHENIDATE HYDROCHLORIDE (298-59-9)
Methylphenidate · Ritalin · Concerta
Score:
#43 in Neurology
,
#231 in Neuroscience
,
#1073 in Biology
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- Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man (Clinical Pharmacology & Therapeutics, 1971)
- Dopamine Transporter Occupancies in the Human Brain Induced by Therapeutic Doses of Oral Methylphenidate (American Journal of Psychiatry, 1998)
- Selective effects of methylphenidate in attention deficit hyperactivity disorder: A functional magnetic resonance study (Proceedings of the National Academy of Sciences of the United States of America, 1998)
- Therapeutic Doses of Oral Methylphenidate Significantly Increase Extracellular Dopamine in the Human Brain (The Journal of Neuroscience, 2001)
- Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine. (Journal of Neurochemistry, 2002)
- Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography. (Neuroscience Letters, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Methylphenidate
- Ritalin
- Concerta
- Metadate
- Methylin
- Ritalin SR
- Daytrana
- Mallinckrodt Brand of Methylphenidate Hydrochloride
- Celltech Brand of Methylphenidate Hydrochloride
- Centedrin
- Cephalon Brand of Methylphenidate Hydrochloride
- Novartis Brand 2 of Methylphenidate Hydrochloride
- Phenidylate
- Ritaline
- Tsentedrin
- Novartis Brand 1 of Methylphenidate Hydrochloride
- Equasym
- Ritalin-SR
-
SMILESCOC(=O)C(C1CCCCN1)C2=CC=CC=C2.Cl
-
InChIKeyJUMYIBMBTDDLNG-UHFFFAOYSA-N
- Pubchem - METHYLPHENIDATE HYDROCHLORIDE
- Wikipedia - methylphenidate hydrochloride
Methylphenidate, sold under various trade names, Ritalin being one of the most commonly known, is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. The original patent was owned by CIBA, now Novartis Corporation. It was first licensed by the US Food and Drug Administration (FDA) in 1955 for treating what was then known as hyperactivity.
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Synthesis
benzene
+
Reactant
(Friedel-Crafts alkylation)
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(550-99-2)
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(90-41-5)
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(7005-72-3)
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(36282-47-0, 53611-16-8)
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(16595-80-5)
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(28322-02-3)
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(1928-38-7)
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(1205-08-9)
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(321-60-8)
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(5440-27-7)
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(1754-62-7, 103-26-4)
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(43121-43-3)
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(3506-09-0, 318-98-9)
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(92-67-1)
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(101-84-8)
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(122-66-7, 38622-18-3)
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METHYLPHENIDATE HYDROCHLORIDE
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