| Weight | 283.799 g/mol |
|---|---|
| Formula | C15H22ClNO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
Pethidine hydrochloride (50-13-5)
Meperidine · Demerol · Dolin
Score:
#33 in Neurology
,
#174 in Neuroscience
,
#847 in Biology
,
#936 in Chemistry
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- Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis (Science, 1983)
- The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. (Pain, 1977)
- Chronic parkinsonism secondary to intravenous injection of meperidine analogues (Psychiatry Research-neuroimaging, 1979)
- THE EVALUATION OF THE ANALGESIC ACTION OF PETHIDINE HYDROCHLORIDE (DEMEROL) (Journal of Pharmacology and Experimental Therapeutics, 1944)
- Central nervous system excitatory effects of meperidine in cancer patients (Annals of Neurology, 1983)
- THE EFFECTS OF MORPHINE, METHADONE AND MEPERIDINE ON SOME REFLEX RESPONSES OF SPINAL ANIMALS TO NOCICEPTIVE STIMULATION (Journal of Pharmacology and Experimental Therapeutics, 1951)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Meperidine
- Demerol
- Dolin
- Pethidine
- Meperidine Hydrochloride
- Dolantin
- Dolosal
- Dolargan
- Lydol
- Operidine EPJ-I
- Operidine EPJ I
- Dolsin
- Dolcontral
- Lidol
- Isonipecain
-
SMILESCCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2.Cl
-
InChIKeyWCNLCIJMFAJCPX-UHFFFAOYSA-N
- Pubchem - Pethidine hydrochloride
- Wikipedia - meperidine hydrochloride
Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class. Synthesized in 1939 as a potential anticholinergic agent by the German chemist Otto Eisleb, its analgesic properties were first recognized by Otto Schaumann while working for IG Farben, Germany. Pethidine is the prototype of a large family of analgesics including the pethidine 4-phenylpiperidines (piminodine, anileridine and others), the prodines (alphaprodine, MPPP, etc.), bemidones (ketobemidone, etc.) and others more distant, including diphenoxylate and analogues.
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Synthesis
benzene
+
Reactant
(Friedel-Crafts alkylation)
Similar Compounds
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(4075-79-0)
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(5411-22-3)
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(27323-18-8, 11097-69-1, 2051-60-7, 53469-21-9)
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(1867-66-9)
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FENOXYCARB
(72490-01-8)
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2 safety hazards
3 suppliers
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(63-92-3)
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2 safety hazards
3 suppliers
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(147-24-0)
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3 safety hazards
3 suppliers
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(77-40-7)
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3 suppliers
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(19486-60-3, 25640-78-2)
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3 suppliers
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(2201-15-2)
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3 suppliers
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(28322-02-3)
16 alternate names
3 suppliers
CYANOFENPHOS
(62421-62-9, 62421-61-8, 62421-63-0, 13067-93-1, 34460-46-3)
16 alternate names
5 safety hazards
3 suppliers
p-Isopropoxydiphenylamine
(101-73-5)
16 alternate names
3 suppliers
methyl 2-(1H-indol-3-yl)acetate
(1912-33-0)
16 alternate names
3 suppliers
10094-34-5
(10094-34-5)
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Carbaryl
(27636-33-5, 3197-92-0, 63-25-2)
16 alternate names
2 safety hazards
3 suppliers
2-Acetamidofluorene
(53-96-3)
16 alternate names
3 suppliers
HEPTENOPHOS
(23560-59-0)
16 alternate names
2 safety hazards
3 suppliers
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(550-99-2)
16 alternate names
3 suppliers
DIPHENAMID
(957-51-7)
16 alternate names
1 safety hazard
3 suppliers
Diphenylmethane
(101-81-5)
16 alternate names
3 suppliers
101-72-4
(101-72-4)
16 alternate names
5 safety hazards
3 suppliers
4-Chlorodiphenyl ether
(7005-72-3)
16 alternate names
3 suppliers
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(92-59-1)
16 alternate names
3 suppliers
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(22306-05-4, 154-69-8)
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3 suppliers
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(67-92-5)
16 alternate names
3 suppliers
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(16595-80-5)
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1 safety hazard
3 suppliers
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(13684-56-5)
16 alternate names
4 safety hazards
3 suppliers
Diethylpropion Hydrochloride
(134-80-5)
16 alternate names
3 suppliers
QUINALPHOS
(13593-03-8)
16 alternate names
5 safety hazards
3 suppliers
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(613-37-6)
16 alternate names
3 suppliers
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(2051-62-9)
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3 suppliers
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(131-53-3)
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3 suppliers
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(782-74-1)
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1 safety hazard
3 suppliers
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(13029-08-8)
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3 suppliers
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(2544-09-4, 6014-30-8)
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(103-29-7, 38888-98-1)
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(151-05-3)
16 alternate names
3 suppliers
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(63-56-9)
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3 suppliers
Benzyl butyl phthalate
(85-68-7)
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3 suppliers
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(61788-42-9, 90-43-7)
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3 suppliers
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(92-52-4, 68409-73-4)
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3 suppliers
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(3506-09-0, 318-98-9)
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Diphenyl oxide
(101-84-8)
16 alternate names
2 safety hazards
3 suppliers
Pethidine hydrochloride
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