| Weight | 364.873 g/mol |
|---|---|
| Formula | C19H25ClN2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 8 |
Labetalol hydrochloride (32780-64-6, 72487-34-4)
Labetalol · Normodyne · Trandate
Score:
#160 in Neurology
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#710 in Neuroscience
,
#3152 in Biology
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#3945 in Chemistry
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- Sigma-Aldrich - Labetalol hydrochloride58.70 - 338.10 USD
- Fisher Scientific - Search for Labetalol hydrochloride
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- Influence of labetalol on cocaine-induced coronary vasoconstriction in humans (The American Journal of Medicine, 1993)
- A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy (Obstetrics & Gynecology, 1987)
- A comparison of no medication versus methyldopa or labetalol in chronic hypertension during pregnancy (American Journal of Obstetrics and Gynecology, 1990)
- Letter: Intravenous labetalol in severe hypertension. (The Lancet, 1975)
- A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug. (British Journal of Clinical Pharmacology, 1976)
- Labetalol Reduces Iodine-131 MIBG Uptake by Pheochromocytoma and Normal Tissues (The Journal of Nuclear Medicine, 1989)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Labetalol
- Normodyne
- Trandate
- Labetolol
- Dilevalol
- AH 5158
- Labetalol, (R,R)-Isomer
- R,R Labetalol
- Presolol
- Apo Labetalol
- Apo-Labetalol
- ApoLabetalol
- AH-5158
- AH5158
- Albetol
- SCH 19927
- SCH-19927
- R,R-Labetalol
- SCH19927
-
SMILESCC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl
-
InChIKeyWQVZLXWQESQGIF-UHFFFAOYSA-N
- Pubchem - Labetalol hydrochloride
- Wikipedia - labetalol hydrochloride
Labetalol is a medication used to treat high blood pressure. It can be given intravenously in severe hypertensive situations, or by mouth for long term hypertension management. Its dose and use is limited by its main side effectpostural hypotension, where there is a substantial drop in blood pressure when standing up.
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Synthesis
Reactant
+
Benzene, (3-chlorobutyl)
(Alkylation of primary amines)
Reactant
+
1-Methyl-3-phenylpropylamine
(Reductive amination)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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Labetalol hydrochloride
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