| Weight | 257.765 g/mol |
|---|---|
| Formula | C12H20ClN3O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
Procarbazine hydrochloride (366-70-1)
Procarbazine · Matulane · Natulan
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- A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. (British Journal of Cancer, 2000)
- Adjuvant procarbazine, lomustine, and vincristine improves progression-free survival but not overall survival in newly diagnosed anaplastic oligodendrogliomas and oligoastrocytomas: a randomized European Organisation for Research and Treatment of Cancer phase III trial. (Journal of Clinical Oncology, 2006)
- NOA-04 Randomized Phase III Trial of Sequential Radiochemotherapy of Anaplastic Glioma With Procarbazine, Lomustine, and Vincristine or Temozolomide (Journal of Clinical Oncology, 2009)
- Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Newly Diagnosed Anaplastic Oligodendroglioma: Long-Term Follow-Up of EORTC Brain Tumor Group Study 26951 (Journal of Clinical Oncology, 2013)
- Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma. (Cancer treatment reports, 1983)
- Phase II Trial of Procarbazine, Lomustine, and Vincristine as Initial Therapy for Patients With Low-Grade Oligodendroglioma or Oligoastrocytoma: Efficacy and Associations With Chromosomal Abnormalities (Journal of Clinical Oncology, 2003)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Procarbazine
- Matulane
- Natulan
- Procarbazine Monohydrobromide
- Procarbazine Monohydrochloride
-
SMILESCC(C)NC(=O)C1=CC=C(C=C1)CNNC.Cl
-
InChIKeyDERJYEZSLHIUKF-UHFFFAOYSA-N
- Pubchem - Procarbazine hydrochloride
- Wikipedia - procarbazine hydrochloride
Procarbazine is a chemotherapy medication used for the treatment of Hodgkin's lymphoma and brain cancers. For Hodgkin's it is often used together with mechlorethamine, vincristine, and prednisone while for brain cancers such as glioblastoma multiforme it is used with lomustine and vincristine. It is typically taken by mouth.
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ISOPROPYLAMINE
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Procarbazine hydrochloride
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