Weight | 307.221 g/mol |
---|---|
Formula | C13H20Cl2N2O2 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 6 |
Chloroprocaine hydrochloride (3858-89-7)
chloroprocaine · Nesacaine · chlor-procaine
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- Persistent neurologic deficit and adhesive arachnoiditis following intrathecal 2-chloroprocaine injection. (Anesthesia & Analgesia, 1980)
- Prolonged neural blockade following regional analgesia with 2-chloroprocaine. (Anesthesia & Analgesia, 1980)
- NEUROLOGICAL TOXICITY OF THE SUBARACHNOID INFUSION OF BUPIVACAINE, LIGNOCAINE OR 2-CHLOROPROCAINE IN THE RAT (BJA: British Journal of Anaesthesia, 1985)
- Chronic Neurological Deficits and Nesacaine-CE-An Effect of the Anesthetic, 2-Chloroprocaine, or the Antioxidant, Sodium Bisulfite? (Anesthesia & Analgesia, 1984)
- Maternal, fetal, and neonatal responses after epidural anesthesia with Bupivacaine, 2-Chloroprocaine, or Lidocaine (Anesthesia & Analgesia, 1982)
- Continuous infusion epidural analgesia in parturients receiving bupivacaine, chloroprocaine, or lidocaine--maternal, fetal, and neonatal effects. (Anesthesia & Analgesia, 1984)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - chloroprocaine
- Nesacaine
- chlor-procaine
- 2-chloroprocaine
- Nesacaine MPF
-
SMILESCCN(CC)CCOC(=O)C1=C(C=C(C=C1)N)Cl.Cl
-
InChIKeySZKQYDBPUCZLRX-UHFFFAOYSA-N
- Pubchem - Chloroprocaine hydrochloride
- Wikipedia - chloroprocaine hydrochloride
Chloroprocaine (trade name Nesacaine, Nesacaine-MPF) (often in the hydrochloride salt form as the aforementioned trade names) is a local anesthetic given by injection during surgical procedures and labor and delivery. Chloroprocaine vasodilates; this is in contrast to cocaine which vasoconstrics. Chloroprocaine is an ester anesthetic.
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Synthesis
Ethylboronic acid
+
Reactant
(Chan-Lam coupling reaction)
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