| Weight | 264.281 g/mol |
|---|---|
| Formula | C13H16N2O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
AFMK (52450-38-1)
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- On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK (Journal of Pineal Research, 2013)
- Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages (Journal of Neuroimmunology, 2005)
- AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice (Journal of Pineal Research, 2007)
- Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite, AFMK. (Journal of Pineal Research, 2008)
- Radioimmunoassay of N-acetyl-N-formyl-5 -methoxykynuramine (AFMK): a melatonin oxidative metabolite (Life Sciences, 2003)
- ArenePerfluoroarene Interactions as Physical Cross-Links for Hydrogel Formation We thank the Office of Naval Research for funding this work. AFMK thanks the Humboldt-Foundation for a Feodor-Lynen Fellowship. We thank Rob Lammertink for help with the rheology measurements. (Angewandte Chemie, 2002)
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SMILESCC(=O)NCCC(=O)C1=C(C=CC(=C1)OC)NC=O
-
InChIKeyJYWNYMJKURVPFH-UHFFFAOYSA-N
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Synthesis
acetamide
+
Reactant
(Alkylation of primary amines)
N-(4-Methoxyphenyl)formamide
+
Reactant
(Friedel-Crafts acylation)
Reactant
+
N-(2-Chloroethyl)acetamide
(Grignard carbonyl)
Reactant
+
Formylaminoradical
(Chan-Lam coupling reaction)
Reactant
+
Methyl hydroperoxide
(Dakin oxidation)
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