| Weight | 327.852 g/mol |
|---|---|
| Formula | C17H26ClNO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
CYCLOPENTOLATE HYDROCHLORIDE (5870-29-1)
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- Acute psychosis associated with topical cyclopentolate hydrochloride (American Journal of Ophthalmology, 1988)
- 1% Cyclopentolate hydrochloride : another look at the time course of cycloplegia using an objective measure of the accommodative response (Optometry and Vision Science, 1993)
- Possible allergic reactions to cyclopentolate hydrochloride: case reports with literature review of uses and adverse reactions (Ophthalmic and Physiological Optics, 1991)
- Separate and additive mydriatic effects of lidocaine hydrochloride, phenylephrine, and cyclopentolate after intracameral injection. (Journal of Cataract and Refractive Surgery, 2008)
- Grand Mal Seizure in a Child 30 Minutes After Cyclogyl (Cyclopentolate Hydrochloride) and 10% Neo-Synephrine (Phenylephrine Hydrochloride) Eye Drops Were Instilled (Pediatrics, 2004)
- Adverse systemic reactions of topical cyclopentolate hydrochloride. (Annals of Ophthalmology, 1976)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN(C)CCOC(=O)C(C1=CC=CC=C1)C2(CCCC2)O.Cl
-
InChIKeyRHKZVMUBMXGOLL-UHFFFAOYSA-N
- Pubchem - CYCLOPENTOLATE HYDROCHLORIDE
- Wikipedia - cyclopentolate hydrochloride
Cyclopentolate is a medication commonly used during pediatric eye examinations that dilates the eye (mydriatic), prevents accommodation of the eye to different distances (cycloplegic), and blocks specific receptors called muscarinic receptors (muscarinic antagonist). Cyclopentolate is also administered as an atropine substitute to reverse muscarinic and central nervous system effects of indirect cholinomimetic (anti-AChase) administration. When used in eye drops in paediatric eye examinations, cyclopentolate 0.5 percent and 1.0 percent is used to stop the eye focusing at any distance closer than infinity.
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Synthesis
Reactant
+
CYCLOPENTANONE
(Reformatsky reaction)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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CYCLOPENTOLATE HYDROCHLORIDE
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