| Weight | 313.869 g/mol |
|---|---|
| Formula | C17H28ClNO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
Venlafaxine hydrochloride (99300-78-4)
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- Pilot evaluation of venlafaxine hydrochloride for the therapy of hot flashes in cancer survivors. (Journal of Clinical Oncology, 1998)
- Brain Blood Flow Changes in Depressed Patients Treated With Interpersonal Psychotherapy or Venlafaxine Hydrochloride: Preliminary Findings (Archives of General Psychiatry, 2001)
- Management of postmenopausal hot flushes with venlafaxine hydrochloride: A randomized, controlled trial (Obstetrics & Gynecology, 2005)
- A Randomized, Placebo-Controlled, Dose-Response Trial of Venlafaxine Hydrochloride in the Treatment of Major Depression (The Journal of Clinical Psychiatry, 1998)
- The safety and tolerability of venlafaxine hydrochloride: analysis of the clinical trials database. (Journal of Clinical Psychopharmacology, 1996)
- Venlafaxine hydrochloride (Effexor) relieves thermal hyperalgesia in rats with an experimental mononeuropathy (Pain, 1996)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl
-
InChIKeyQYRYFNHXARDNFZ-UHFFFAOYSA-N
- Pubchem - Venlafaxine hydrochloride
- Wikipedia - venlafaxine hydrochloride
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant of the selective serotonin-norepinephrine reuptake inhibitor (SNRI) class. This means it increases the concentrations of the neurotransmitters serotonin and norepinephrine in the body and the brain. First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
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Synthesis
ANISOLE
+
Reactant
(Friedel-Crafts alkylation)
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Venlafaxine hydrochloride
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