Weight | 377.912 g/mol |
---|---|
Formula | C21H28ClNO3 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 11 |
PROPAFENONE HYDROCHLORIDE
Propafenone · Rythmol · Nistaken
34183-22-7, 107381-35-1, 107381-36-2
Score:
#1522 in Biochemistry
,
#3539 in Biology
,
#4439 in Chemistry
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- Sigma-Aldrich - PROPAFENONE HYDROCHLORIDE105.50 - 338.10 USD
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- Polymorphism of propafenone metabolism and disposition in man: clinical and pharmacokinetic consequences. (Circulation, 1987)
- Propafenone versus sotalol for suppression of recurrent symptomatic atrial fibrillation (American Journal of Cardiology, 1993)
- Effects of oral propafenone administration before electrical cardioversion of chronic atrial fibrillation: a placebo-controlled study. (Journal of the American College of Cardiology, 1996)
- Clinical pharmacology of propafenone. (Circulation, 1983)
- K+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes. (Journal of Pharmacology and Experimental Therapeutics, 1994)
- Conversion of recent-onset atrial fibrillation by a single oral loading dose of propafenone or flecainide. (American Journal of Cardiology, 1994)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Propafenone
- Rythmol
- Nistaken
- SA 79
- Jutanorm
- SA-79
- Rytmonorm
- Arythmol
- Apo-Propafenone
- Fenoprain
- Rytmogenat
- Propafenone, (+-)-Isomer
- Pintoform
- Propafenon AL
- Rytmo-Puren
- Propafenone Hydrochloride, (S)-Isomer
- Propafenon Minden
- Propafenone, (S)-Isomer
- Propafenone Hydrochloride, (R)-Isomer
- SA79
- Norfenon
- Propafenon Hexal
- Prolecofen
- Propafenone, (R)-Isomer
- Baxarytmon
- Propamerck
- Cuxafenon
-
SMILESCCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl
-
InChIKeyXWIHRGFIPXWGEF-UHFFFAOYSA-N
- Pubchem - PROPAFENONE HYDROCHLORIDE
- Wikipedia - propafenone hydrochloride
Propafenone ( proh-PAF-i-nohn; brand name Rythmol SR or Rytmonorm) is a class 1C anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.
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Synthesis
Reactant
+
(2-Chloroethyl)benzene
(Grignard carbonyl)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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