Ritodrine hydrochloride (26652-09-5, 23239-51-2)

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Suppliers

• 

  250 mg
  $50.00

  500 mg
  $75.00

  1 g
  $120.00

  2 g
  $225.00

  5 g
  $525.00

Most-cited Publications

• Treatment of preterm labor with the beta-adrenergic agonist ritodrine [2] (The New England Journal of Medicine, 1992)
• Nifedipine and ritodrine in the management of preterm labor: A randomized multicenter trial (Obstetrics & Gynecology, 1997)
• Double-blind, randomized, controlled trial of atosiban and ritodrine in the treatment of preterm labor: A multicenter effectiveness and safety study (American Journal of Obstetrics and Gynecology, 2000)
• Results of Double-blind, Multicentre Study with Ritodrine in Premature Labour (BMJ, 1971)
• A comparison of tocolysis with nifedipine or ritodrine: Analysis of efficacy and maternal, fetal, and neonatal outcome (American Journal of Obstetrics and Gynecology, 1990)
• Randomized comparative trial of indomethacin and ritodrine for the long-term treatment of preterm labor. (American Journal of Obstetrics and Gynecology, 1991)

Areas of Application

Safety

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Trends

Alternate Names

• Ritodrine
• PrePar
• Yutopar
• Pre Par
• DU21220
• Pre-Par
• DU-21220
• DU 21220
• SMILES
  CC(C(C1=CC=C(C=C1)O)O)NCCC2=CC=C(C=C2)O.Cl
• InChIKey
  IDLSITKDRVDKRV-UHFFFAOYSA-N

External Links

• Pubchem - Ritodrine hydrochloride
• Wikipedia - ritodrine
  Ritodrine (trade name Yutopar) is a tocolytic drug used to stop premature labor. This drug has been removed from the US market, according to FDA Orange Book. It was available in oral tablets or as an injection and was typically used as the hydrochloride salt, ritodrine hydrochloride.

Synthesis

Phenol  +  4-[2-(2-Chloroethylamino)-1-hydroxypropyl]phenol (Friedel-Crafts alkylation)

2-(4-Hydroxyphenyl)acetaldehyde  +  p-HYDROXYNOREPHEDRINE (Reductive amination)

Reactant  +  4-CHLOROPHENOL (Grignard alcohol)

tyramine  +  Reactant (Alkylation of primary amines)

Synthesis of Ritodrine hydrochloride ›

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Ritodrine hydrochloride

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